Elimination of unaltered DNA in mixed clinical samples via nuclease-assisted minor-allele enrichment
Presence of excess unaltered, wild-type (WT) DNA providing no information of biological or clinical value often masks rare alterations containing diagnostic or therapeutic clues in cancer, prenatal diagnosis, infectious diseases or organ transplantation. With the surge of high-throughput technologie...
| Hoofdauteurs: | , , , , , , |
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| Formaat: | Journal article |
| Gepubliceerd in: |
Oxford University Press
2016
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