The FT210 cell line is a mouse G2 phase mutant with a temperature-sensitive CDC2 gene product.

The FT210 cell line is a mouse G2 phase mutant with a temperature-sensitive CDC2 gene product.

The mouse cell FT210 was isolated as a G2 phase mutant with a possible defect in the histone H1 kinase. We determined that a temperature-sensitive lesion in this cell line lies in the CDC2 gene. DNA sequence analysis revealed two point mutations in highly conserved regions of the gene: an isoleucine...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser:	Th'ng, J, Wright, P, Hamaguchi, J, Lee, MG, Norbury, C, Nurse, P, Bradbury, E
Format:	Journal article
Sprache:	English
Veröffentlicht:	1990

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