TDP-43 pathological changes in early onset familial and sporadic Alzheimer's disease, late onset Alzheimer's disease and Down's syndrome: association with age, hippocampal sclerosis and clinical phenotype.

TDP-43 pathological changes in early onset familial and sporadic Alzheimer's disease, late onset Alzheimer's disease and Down's syndrome: association with age, hippocampal sclerosis and clinical phenotype.

TDP-43 immunoreactive (TDP-43-ir) pathological changes were investigated in the temporal cortex and hippocampus of 11 patients with autosomal dominant familial forms of Alzheimer's disease (FAD), 169 patients with sporadic AD [85 with early onset disease (EOAD) (i.e before 65 years of age), and...

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Main Authors: Davidson, Y, Raby, S, Foulds, P, Robinson, A, Thompson, J, Sikkink, S, Yusuf, I, Amin, H, DuPlessis, D, Troakes, C, Al-Sarraj, S, Sloan, C, Esiri, M, Prasher, V, Allsop, D, Neary, D, Pickering-Brown, S, Snowden, J, Mann, D
Format: Journal article
Language:English
Published: 2011

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