Six-year experience of detection and investigation of possible Middle East Respiratory Syndrome coronavirus cases, England, 2012-2018

Objectives Surveillance for Middle East Respiratory Syndrome (MERS) has been undertaken in the UK since September 2012. This study describes the surveillance outcomes in England from 2012 to 2018. Study design This was a descriptive study using surveillance data. Methods Local health protection te...

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Bibliographic Details
Main Authors: Zhao, H, ParryFord, F, Dabrera, G, Sinnathamby, M, Ellis, J, Dunning, WJ, Osman, H, Machin, N, Pebody, R
Format: Journal article
Language:English
Published: Elsevier 2020
Description
Summary:Objectives Surveillance for Middle East Respiratory Syndrome (MERS) has been undertaken in the UK since September 2012. This study describes the surveillance outcomes in England from 2012 to 2018. Study design This was a descriptive study using surveillance data. Methods Local health protection teams in England report possible MERS cases to the National Infection Service with clinical and laboratory data. Results A total of 1301 possible MERS cases were identified in the study period. Five cases were laboratory-confirmed MERS. The majority of cases had travelled to Saudi Arabia (56.7%) and United Arab Emirates (25.9%). Fifty-four percent of cases were men and 43.7% were women. The majority of cases (65.1%) were aged 45 years or older. The number of tests increased in the period after Hajj each year. Laboratory-confirmed alternative diagnoses were available for 513 (39.4%) cases; influenza was the most common virus detected (n = 255, 52.4%). Conclusions Our study highlights the importance of differential diagnosis of influenza and other respiratory pathogens and early influenza antiviral treatment.