Six-year experience of detection and investigation of possible Middle East Respiratory Syndrome coronavirus cases, England, 2012-2018
Objectives Surveillance for Middle East Respiratory Syndrome (MERS) has been undertaken in the UK since September 2012. This study describes the surveillance outcomes in England from 2012 to 2018. Study design This was a descriptive study using surveillance data. Methods Local health protection te...
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Journal article |
| Language: | English |
| Published: |
Elsevier
2020
|
| _version_ | 1797083688485257216 |
|---|---|
| author | Zhao, H ParryFord, F Dabrera, G Sinnathamby, M Ellis, J Dunning, WJ Osman, H Machin, N Pebody, R |
| author_facet | Zhao, H ParryFord, F Dabrera, G Sinnathamby, M Ellis, J Dunning, WJ Osman, H Machin, N Pebody, R |
| author_sort | Zhao, H |
| collection | OXFORD |
| description | Objectives
Surveillance for Middle East Respiratory Syndrome (MERS) has been undertaken in the UK since September 2012. This study describes the surveillance outcomes in England from 2012 to 2018.
Study design
This was a descriptive study using surveillance data.
Methods
Local health protection teams in England report possible MERS cases to the National Infection Service with clinical and laboratory data.
Results
A total of 1301 possible MERS cases were identified in the study period. Five cases were laboratory-confirmed MERS. The majority of cases had travelled to Saudi Arabia (56.7%) and United Arab Emirates (25.9%). Fifty-four percent of cases were men and 43.7% were women. The majority of cases (65.1%) were aged 45 years or older. The number of tests increased in the period after Hajj each year. Laboratory-confirmed alternative diagnoses were available for 513 (39.4%) cases; influenza was the most common virus detected (n = 255, 52.4%).
Conclusions
Our study highlights the importance of differential diagnosis of influenza and other respiratory pathogens and early influenza antiviral treatment.
|
| first_indexed | 2024-03-07T01:44:59Z |
| format | Journal article |
| id | oxford-uuid:981ca087-eeeb-491f-a8f0-b3b235a9e58a |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T01:44:59Z |
| publishDate | 2020 |
| publisher | Elsevier |
| record_format | dspace |
| spelling | oxford-uuid:981ca087-eeeb-491f-a8f0-b3b235a9e58a2022-03-27T00:04:46ZSix-year experience of detection and investigation of possible Middle East Respiratory Syndrome coronavirus cases, England, 2012-2018Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:981ca087-eeeb-491f-a8f0-b3b235a9e58aEnglishSymplectic ElementsElsevier2020Zhao, HParryFord, FDabrera, GSinnathamby, MEllis, JDunning, WJOsman, HMachin, NPebody, RObjectives Surveillance for Middle East Respiratory Syndrome (MERS) has been undertaken in the UK since September 2012. This study describes the surveillance outcomes in England from 2012 to 2018. Study design This was a descriptive study using surveillance data. Methods Local health protection teams in England report possible MERS cases to the National Infection Service with clinical and laboratory data. Results A total of 1301 possible MERS cases were identified in the study period. Five cases were laboratory-confirmed MERS. The majority of cases had travelled to Saudi Arabia (56.7%) and United Arab Emirates (25.9%). Fifty-four percent of cases were men and 43.7% were women. The majority of cases (65.1%) were aged 45 years or older. The number of tests increased in the period after Hajj each year. Laboratory-confirmed alternative diagnoses were available for 513 (39.4%) cases; influenza was the most common virus detected (n = 255, 52.4%). Conclusions Our study highlights the importance of differential diagnosis of influenza and other respiratory pathogens and early influenza antiviral treatment. |
| spellingShingle | Zhao, H ParryFord, F Dabrera, G Sinnathamby, M Ellis, J Dunning, WJ Osman, H Machin, N Pebody, R Six-year experience of detection and investigation of possible Middle East Respiratory Syndrome coronavirus cases, England, 2012-2018 |
| title | Six-year experience of detection and investigation of possible Middle East Respiratory Syndrome coronavirus cases, England, 2012-2018 |
| title_full | Six-year experience of detection and investigation of possible Middle East Respiratory Syndrome coronavirus cases, England, 2012-2018 |
| title_fullStr | Six-year experience of detection and investigation of possible Middle East Respiratory Syndrome coronavirus cases, England, 2012-2018 |
| title_full_unstemmed | Six-year experience of detection and investigation of possible Middle East Respiratory Syndrome coronavirus cases, England, 2012-2018 |
| title_short | Six-year experience of detection and investigation of possible Middle East Respiratory Syndrome coronavirus cases, England, 2012-2018 |
| title_sort | six year experience of detection and investigation of possible middle east respiratory syndrome coronavirus cases england 2012 2018 |
| work_keys_str_mv | AT zhaoh sixyearexperienceofdetectionandinvestigationofpossiblemiddleeastrespiratorysyndromecoronaviruscasesengland20122018 AT parryfordf sixyearexperienceofdetectionandinvestigationofpossiblemiddleeastrespiratorysyndromecoronaviruscasesengland20122018 AT dabrerag sixyearexperienceofdetectionandinvestigationofpossiblemiddleeastrespiratorysyndromecoronaviruscasesengland20122018 AT sinnathambym sixyearexperienceofdetectionandinvestigationofpossiblemiddleeastrespiratorysyndromecoronaviruscasesengland20122018 AT ellisj sixyearexperienceofdetectionandinvestigationofpossiblemiddleeastrespiratorysyndromecoronaviruscasesengland20122018 AT dunningwj sixyearexperienceofdetectionandinvestigationofpossiblemiddleeastrespiratorysyndromecoronaviruscasesengland20122018 AT osmanh sixyearexperienceofdetectionandinvestigationofpossiblemiddleeastrespiratorysyndromecoronaviruscasesengland20122018 AT machinn sixyearexperienceofdetectionandinvestigationofpossiblemiddleeastrespiratorysyndromecoronaviruscasesengland20122018 AT pebodyr sixyearexperienceofdetectionandinvestigationofpossiblemiddleeastrespiratorysyndromecoronaviruscasesengland20122018 |