Hippo tumour suppressor and Hedgehog pathway crosstalk at the primary cilia

<p>Inappropriate activation of the Hedgehog signalling pathway is implicated in broad range of cancers, particularly basal cell carcinoma and medulloblastoma. Recent attempts to target Hedgehog signalling clinically have yielded mixed patient responses, highlighting the need for further study...

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Bibliographic Details
Main Author: Traynor, E
Other Authors: O'Neill, E
Format: Thesis
Language:English
Published: 2017
Subjects: