Fast analysis method for non-invasive imaging of blood flow using vessel-encoded arterial spin labelling

Arterial spin labelling (ASL) MRI offers a non-invasive means to create blood-borne contrast in vivo for dynamic angiographic imaging. By spatial modulation of the ASL process it is possible to uniquely label individual arteries over a series of measurements, allowing each to be separately identifie...

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Main Authors: Chappell, M, Woolrich, M, Okell, T
Format: Patent
Published: United States Patent and Trademark Office 2017
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author Chappell, M
Woolrich, M
Okell, T
author_facet Chappell, M
Woolrich, M
Okell, T
author_sort Chappell, M
collection OXFORD
description Arterial spin labelling (ASL) MRI offers a non-invasive means to create blood-borne contrast in vivo for dynamic angiographic imaging. By spatial modulation of the ASL process it is possible to uniquely label individual arteries over a series of measurements, allowing each to be separately identified in the resulting images. This separation requires appropriate analysis for which a general framework has previously been proposed. Here the general framework is modified for fast analysis of non-invasive imaging of blood flow using vessel encoded arterial spin labelling (VE-ASL). This specifically addresses the issues of computational speed of the analysis and the robustness required to deal with real patient data. The modification applies various approaches for estimation of one or more parameters that change the way a vessel, for example an artery, is encoded to provide the fast analysis.
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spelling oxford-uuid:984b06df-1bb8-44ec-a9fa-b62ddd2a78cd2022-03-27T00:05:54ZFast analysis method for non-invasive imaging of blood flow using vessel-encoded arterial spin labellingPatenthttp://purl.org/coar/resource_type/c_15cduuid:984b06df-1bb8-44ec-a9fa-b62ddd2a78cdSymplectic Elements at OxfordUnited States Patent and Trademark Office2017Chappell, MWoolrich, MOkell, TArterial spin labelling (ASL) MRI offers a non-invasive means to create blood-borne contrast in vivo for dynamic angiographic imaging. By spatial modulation of the ASL process it is possible to uniquely label individual arteries over a series of measurements, allowing each to be separately identified in the resulting images. This separation requires appropriate analysis for which a general framework has previously been proposed. Here the general framework is modified for fast analysis of non-invasive imaging of blood flow using vessel encoded arterial spin labelling (VE-ASL). This specifically addresses the issues of computational speed of the analysis and the robustness required to deal with real patient data. The modification applies various approaches for estimation of one or more parameters that change the way a vessel, for example an artery, is encoded to provide the fast analysis.
spellingShingle Chappell, M
Woolrich, M
Okell, T
Fast analysis method for non-invasive imaging of blood flow using vessel-encoded arterial spin labelling
title Fast analysis method for non-invasive imaging of blood flow using vessel-encoded arterial spin labelling
title_full Fast analysis method for non-invasive imaging of blood flow using vessel-encoded arterial spin labelling
title_fullStr Fast analysis method for non-invasive imaging of blood flow using vessel-encoded arterial spin labelling
title_full_unstemmed Fast analysis method for non-invasive imaging of blood flow using vessel-encoded arterial spin labelling
title_short Fast analysis method for non-invasive imaging of blood flow using vessel-encoded arterial spin labelling
title_sort fast analysis method for non invasive imaging of blood flow using vessel encoded arterial spin labelling
work_keys_str_mv AT chappellm fastanalysismethodfornoninvasiveimagingofbloodflowusingvesselencodedarterialspinlabelling
AT woolrichm fastanalysismethodfornoninvasiveimagingofbloodflowusingvesselencodedarterialspinlabelling
AT okellt fastanalysismethodfornoninvasiveimagingofbloodflowusingvesselencodedarterialspinlabelling