Genome-wide association and epidemiological analyses reveal common genetic origins between uterine leiomyomata and endometriosis

Uterine leiomyomata (UL) are the most common neoplasms of the female reproductive tract and primary cause for hysterectomy, leading to considerable morbidity and high economic burden. Here we conduct a GWAS meta-analysis in 35,474 cases and 267,505 female controls of European ancestry, identifying e...

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Detalhes bibliográficos
Principais autores: Gallagher, CS, Mäkinen, N, Harris, HR, Rahmioglu, N, Uimari, O, Cook, JP, Shigesi, N, Ferreira, T, Velez-Edwards, DR, Edwards, TL, Mortlock, S, Ruhioglu, Z, Day, F, Becker, CM, Karhunen, V, Martikainen, H, Järvelin, M-R, Cantor, RM, Ridker, PM, Terry, KL, Buring, JE, Gordon, SD, Medland, SE, Montgomery, GW, Nyholt, DR
Formato: Journal article
Idioma:English
Publicado em: Nature Research 2019