Genome-wide association and epidemiological analyses reveal common genetic origins between uterine leiomyomata and endometriosis

Uterine leiomyomata (UL) are the most common neoplasms of the female reproductive tract and primary cause for hysterectomy, leading to considerable morbidity and high economic burden. Here we conduct a GWAS meta-analysis in 35,474 cases and 267,505 female controls of European ancestry, identifying e...

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Main Authors: Gallagher, CS, Mäkinen, N, Harris, HR, Rahmioglu, N, Uimari, O, Cook, JP, Shigesi, N, Ferreira, T, Velez-Edwards, DR, Edwards, TL, Mortlock, S, Ruhioglu, Z, Day, F, Becker, CM, Karhunen, V, Martikainen, H, Järvelin, M-R, Cantor, RM, Ridker, PM, Terry, KL, Buring, JE, Gordon, SD, Medland, SE, Montgomery, GW, Nyholt, DR
Format: Journal article
Jezik:English
Izdano: Nature Research 2019