Novel rheumatoid arthritis susceptibility locus at 22q12 identified in an extended UK genome-wide association study.

Novel rheumatoid arthritis susceptibility locus at 22q12 identified in an extended UK genome-wide association study.

OBJECTIVE: The number of confirmed rheumatoid arthritis (RA) loci currently stands at 32, but many lines of evidence indicate that expansion of existing genome-wide association studies (GWAS) enhances the power to detect additional loci. This study was undertaken to extend our previous RA GWAS in a...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون:	Orozco, G, Viatte, S, Bowes, J, Martin, P, Wilson, A, Morgan, A, Steer, S, Wordsworth, P, Hocking, L, Barton, A, Worthington, J, Eyre, S
التنسيق:	Journal article
اللغة:	English
منشور في:	John Wiley and Sons Inc. 2014

مواد مشابهة

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PADI4 genotype is not associated with rheumatoid arthritis in a large UK Caucasian population.
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Association of CD40 with rheumatoid arthritis confirmed in a large UK case-control study.
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No evidence for association of the KLF12 gene with rheumatoid arthritis in a large UK cohort.
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Corrigendum: Identification of AF4/FMR2 family, member 3 (AFF3) as a novel rheumatoid arthritis susceptibility locus and confirmation of two further pan-autoimmune susceptibility genes
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منشور في: (2010)

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منشور في: (2013)

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Reevaluation of the Interaction Between HLA-DRB1 Shared Epitope Alleles, PTPN22, and Smoking in Determining Susceptibility to Autoantibody-Positive and Autoantibody-Negative Rheumatoid Arthritis in a Large UK Caucasian Population (vol 60, pg 2565, 2009)
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منشور في: (2011)

Combined effects of three independent SNPs greatly increase the risk estimate for RA at 6q23.
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Corrigendum: Combined effects of three independent SNPs greatly increase the risk estimate for RA at 6q23
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A replication study of the UK rheumatoid arthritis whole genome screen.
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14.5 Rheumatoid Arthritis susceptibility loci; STAT4, TRAF1/C5 and 6q23 region, are also associated with Juvenile Idiopathic Arthritis
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حسب: Ian C. Scott, وآخرون
منشور في: (2013-10-01)

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Genotypic variability based association identifies novel non-additive loci DHCR7 and IRF4 in sero-negative rheumatoid arthritis
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The PTPN22 R263Q polymorphism is a risk factor for rheumatoid arthritis in caucasian case-control samples.
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Exclusion of PTEN and 10q22-24 as the susceptibility locus for juvenile polyposis syndrome.
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