Fine-mapping of the 1p11.2 breast cancer susceptibility locus

Fine-mapping of the 1p11.2 breast cancer susceptibility locus

The Cancer Genetic Markers of Susceptibility genome-wide association study (GWAS) originally identified a single nucleotide polymorphism (SNP) rs11249433 at 1p11.2 associated with breast cancer risk. To fine-map this locus, we genotyped 92 SNPs in a 900kb region (120,505,799–121,481,132) flanking rs...

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Main Authors: Horne, H, Chung, C, Zhang, H, Yu, K, Prokunina-Olsson, L, Michailidou, K, Bolla, M, Wang, Q, Dennis, J, Hopper, J, Southey, M, Schmidt, M, Broeks, A, Muir, K, Lophatananon, A, Fasching, P, Beckmann, M, Fletcher, O, Johnson, N, Sawyer, E, Tomlinson, I, Burwinkel, B, Marme, F, Guénel, P, Truong, T, Bojesen, S, Flyger, H, Benitez, J, González-Neira, A, Anton-Culver, H, Neuhausen, S, Brenner, H, Arndt, V, Meindl, A, Schmutzler, R, Brauch, H, Hamann, U, Nevanlinna, H, Khan, S, Matsuo, K, Iwata, H, Dörk, T, Bogdanova, N, Lindblom, A, Margolin, S, Mannermaa, A, Kosma, V, Chenevix-Trench, G, Wu, A, Ven den Berg, D, Smeets, A, Zhao, H, Chang-Claude, J, Rudolph, A, Radice, P, Barile, M, Couch, F, Vachon, C, Giles, G, Milne, R, Haiman, C, Marchand, L, Goldberg, M, Teo, S, Taib, N, Kristensen, V, Borresen-Dale, A, Zheng, W, Shrubsole, M, Winqvist, R, Jukkola-Vuorinen, A, Andrulis, I, Knight, J, Devilee, P, Seynaeve, C, García-Closas, M, Czene, K, Darabi, H, Hollestelle, A, Martens, J, Li, J, Lu, W, Shu, X, Cox, A, Cross, S, Blot, W, Cai, Q, Shah, M, Luccarini, C, Baynes, C, Harrington, P, Kang, D, Choi, J, Hartman, M, Chia, K, Kabisch, M, Torres, D, Jakubowska, A, Lubinski, J, Sangrajrang, S, Brennan, P, Slager, S, Yannoukakos, D, Shen, C, Hou, M, Swerdlow, A, Orr, N, Simard, J, Hall, P, Pharoah, P, Easton, D, Chanock, S, Dunning, A, Figueroa, J
Format: Journal article
Language:English
Published: Public Library of Science 2016

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