Crystal structure of a berenil-dodecanucleotide complex: the role of water in sequence-specific ligand binding.

Crystal structure of a berenil-dodecanucleotide complex: the role of water in sequence-specific ligand binding.

The three-dimensional structure of a complex between the dodecanucleotide d(CGCGAATTCGCG) and the anti-trypanocidal drug berenil, has been determined to a resolution of 2.5 A. The structure has been solved by molecular replacement and refined to an R factor of 0.177. A total of 49 water molecules ha...

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Bibliographic Details
Main Authors:	Brown, D, Sanderson, MR, Skelly, J, Jenkins, T, Brown, T, Garman, E, Stuart, D, Neidle, S
Format:	Journal article
Language:	English
Published:	1990

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