Enhancing quality of life among adolescents with bipolar disorder: A randomized trial of two psychosocial interventions.
<h4>Background</h4> <p>Adolescents with bipolar disorder (BD) report lower quality of life (QoL) than adolescents with other psychiatric disorders. This study compared the efficacy of family-focused therapy for adolescents (FFT-A) plus pharmacotherapy to brief psychoeducation (enh...
| Main Authors: | , , , , , |
|---|---|
| Format: | Journal article |
| Language: | English |
| Published: |
Elsevier
2017
|
| _version_ | 1797083766515040256 |
|---|---|
| author | O'Donnell, L Axelson, D Kowatch, R Schneck, C Sugar, C Miklowitz, D |
| author_facet | O'Donnell, L Axelson, D Kowatch, R Schneck, C Sugar, C Miklowitz, D |
| author_sort | O'Donnell, L |
| collection | OXFORD |
| description | <h4>Background</h4> <p>Adolescents with bipolar disorder (BD) report lower quality of life (QoL) than adolescents with other psychiatric disorders. This study compared the efficacy of family-focused therapy for adolescents (FFT-A) plus pharmacotherapy to brief psychoeducation (enhanced care, or EC) plus pharmacotherapy on self-rated QoL in adolescents with BD over 2 years.</p> <h4>Methods</h4> <p>Participants were 141 adolescents (mean age: 15.6±1.4yr) with BD I or II who had a mood episode in the previous 3 months. Adolescents and parents were randomly assigned to (1) FFT-A, given in 21 sessions in 9 months of psychoeducation, communication enhancement training, and problem-solving skills training, or (2) EC, given in 3 family psychoeducation sessions. Study psychiatrists provided patient participants with protocol-based pharmacotherapy for the duration of the study. QoL was assessed with The KINDLR Questionnaire (Ravens-Sieberer and Bullinger, 1998) during active treatment (baseline to 9 months) and during a post-treatment followup (9–24 months).</p> <h4>Results</h4> <p>The two treatment groups did not differ in overall QoL scores over 24 months. However, adolescents in FFT-A had greater improvements in quality of family relationships and physical well-being than participants in EC. For quality of friendships, the trajectory during active treatment favored EC, whereas the trajectory during post-treatment favored FFT-A.</p> <h4>Limitations</h4> <p>We were unable to standardize medication use or adherence over time. Quality of life was based on self-report rather than on observable functioning.</p> <h4>Conclusions</h4> <p>A short course of family psychoeducation and skills training may enhance relational functioning and health in adolescents with BD. The effects of different psychosocial interventions on peer relationships deserves further study.</p> |
| first_indexed | 2024-03-07T01:46:03Z |
| format | Journal article |
| id | oxford-uuid:9874f212-1f9a-414a-bfea-8e7f3465f7d8 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T01:46:03Z |
| publishDate | 2017 |
| publisher | Elsevier |
| record_format | dspace |
| spelling | oxford-uuid:9874f212-1f9a-414a-bfea-8e7f3465f7d82022-03-27T00:07:04ZEnhancing quality of life among adolescents with bipolar disorder: A randomized trial of two psychosocial interventions.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:9874f212-1f9a-414a-bfea-8e7f3465f7d8EnglishSymplectic Elements at OxfordElsevier2017O'Donnell, LAxelson, DKowatch, RSchneck, CSugar, CMiklowitz, D <h4>Background</h4> <p>Adolescents with bipolar disorder (BD) report lower quality of life (QoL) than adolescents with other psychiatric disorders. This study compared the efficacy of family-focused therapy for adolescents (FFT-A) plus pharmacotherapy to brief psychoeducation (enhanced care, or EC) plus pharmacotherapy on self-rated QoL in adolescents with BD over 2 years.</p> <h4>Methods</h4> <p>Participants were 141 adolescents (mean age: 15.6±1.4yr) with BD I or II who had a mood episode in the previous 3 months. Adolescents and parents were randomly assigned to (1) FFT-A, given in 21 sessions in 9 months of psychoeducation, communication enhancement training, and problem-solving skills training, or (2) EC, given in 3 family psychoeducation sessions. Study psychiatrists provided patient participants with protocol-based pharmacotherapy for the duration of the study. QoL was assessed with The KINDLR Questionnaire (Ravens-Sieberer and Bullinger, 1998) during active treatment (baseline to 9 months) and during a post-treatment followup (9–24 months).</p> <h4>Results</h4> <p>The two treatment groups did not differ in overall QoL scores over 24 months. However, adolescents in FFT-A had greater improvements in quality of family relationships and physical well-being than participants in EC. For quality of friendships, the trajectory during active treatment favored EC, whereas the trajectory during post-treatment favored FFT-A.</p> <h4>Limitations</h4> <p>We were unable to standardize medication use or adherence over time. Quality of life was based on self-report rather than on observable functioning.</p> <h4>Conclusions</h4> <p>A short course of family psychoeducation and skills training may enhance relational functioning and health in adolescents with BD. The effects of different psychosocial interventions on peer relationships deserves further study.</p> |
| spellingShingle | O'Donnell, L Axelson, D Kowatch, R Schneck, C Sugar, C Miklowitz, D Enhancing quality of life among adolescents with bipolar disorder: A randomized trial of two psychosocial interventions. |
| title | Enhancing quality of life among adolescents with bipolar disorder: A randomized trial of two psychosocial interventions. |
| title_full | Enhancing quality of life among adolescents with bipolar disorder: A randomized trial of two psychosocial interventions. |
| title_fullStr | Enhancing quality of life among adolescents with bipolar disorder: A randomized trial of two psychosocial interventions. |
| title_full_unstemmed | Enhancing quality of life among adolescents with bipolar disorder: A randomized trial of two psychosocial interventions. |
| title_short | Enhancing quality of life among adolescents with bipolar disorder: A randomized trial of two psychosocial interventions. |
| title_sort | enhancing quality of life among adolescents with bipolar disorder a randomized trial of two psychosocial interventions |
| work_keys_str_mv | AT odonnelll enhancingqualityoflifeamongadolescentswithbipolardisorderarandomizedtrialoftwopsychosocialinterventions AT axelsond enhancingqualityoflifeamongadolescentswithbipolardisorderarandomizedtrialoftwopsychosocialinterventions AT kowatchr enhancingqualityoflifeamongadolescentswithbipolardisorderarandomizedtrialoftwopsychosocialinterventions AT schneckc enhancingqualityoflifeamongadolescentswithbipolardisorderarandomizedtrialoftwopsychosocialinterventions AT sugarc enhancingqualityoflifeamongadolescentswithbipolardisorderarandomizedtrialoftwopsychosocialinterventions AT miklowitzd enhancingqualityoflifeamongadolescentswithbipolardisorderarandomizedtrialoftwopsychosocialinterventions |