From Brownian Dynamics to Markov Chain: an Ion Channel Example
A discrete rate theory for general multi-ion channels is presented, in which the continuous dynamics of ion diffusion is reduced to transitions between Markovian discrete states. In an open channel, the ion permeation process involves three types of events: an ion entering the channel, an ion escapi...
| Main Authors: | , , |
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| Format: | Journal article |
| Published: |
2012
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