Biological chromodynamics: a general method for measuring protein occupancy across the genome by calibrating ChIP-seq.

Sequencing DNA fragments associated with proteins following in vivo cross-linking with formaldehyde (known as ChIP-seq) has been used extensively to describe the distribution of proteins across genomes. It is not widely appreciated that this method merely estimates a protein's distribution and...

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Bibliografische gegevens
Hoofdauteurs: Hu, B, Petela, N, Kurze, A, Chan, K, Chapard, C, Nasmyth, K
Formaat: Journal article
Taal:English
Gepubliceerd in: Oxford University Press 2015