Rapid parallel acquisition of somatic mutations after NPM1 in acute myeloid leukaemia evolution

Rapid parallel acquisition of somatic mutations after NPM1 in acute myeloid leukaemia evolution

The steps in the progression from subclinical clonal haemopoiesis to acute myeloid leukaemia (AML) have not been defined, nor has its likelihood or latency. NPM1 mutations were not found to drive clonal haemopoiesis in haematologically normal individuals(Genovese et al, 2014; Jaiswal et al, 2014; Xi...

Descrición completa

Detalles Bibliográficos
Main Authors:	Grove, C, Bolli, N, Manes, N, Varela, I, Van't Veer, M, Bench, A, Eldaly, H, Wedge, D, Van Loo, P, Vassiliou, G
Formato:	Journal article
Publicado:	Wiley 2016

Títulos similares

Acute myeloid leukaemia: a paradigm for the clonal evolution of cancer?
por: Carolyn S. Grove, et al.
Publicado: (2014-08-01)

Cup‐like blasts in acute myeloid leukaemia with NPM1 and IDH2 mutations
por: Eiko Ohya, et al.
Publicado: (2021-08-01)

FLT3, NPM1, DNMT3a and NRAS genes mutation in acute myeloid leukaemia in HUSM
por: Mat Yunus, Noraini
Publicado: (2015)

The Clinical Significance Of Npm1, Flt3 And Cebpa Gene Mutations In Adult Patients With Acute Myeloid Leukaemia
por: Ul Haq, Izaz
Publicado: (2020)

Analysis of the clinical impact of NPM1 mutant allele burden in a large cohort of younger adult patients with acute myeloid leukaemia
por: Linch, DC, et al.
Publicado: (2019)

NPM is dood, leve NPM!
por: G. J. Van Helden
Publicado: (2006-11-01)

Molecular characterisation of NPM1 and FLT3-ITD mutations in a central South African adult de novo acute myeloid leukaemia cohort
por: Jean F. Kloppers, et al.
Publicado: (2021-06-01)

Metabolomic profile of acute myeloid leukaemia parallels of prognosis and response to therapy
por: Lukasz Bolkun, et al.
Publicado: (2023-12-01)

FLT3‐targeted therapy restores GATA1 pathway function in NPM1/FLT3‐ITD mutated acute myeloid leukaemia
por: D Sorcini, et al.
Publicado: (2023-11-01)

Clonal structures of leukaemia stem cell populations in myeloid blast phase chronic myeloid leukaemia
por: Karamitros, D, et al.
Publicado: (2016)

Colonic myeloid sarcoma with mutated NPM1 manifesting with ulceration
por: Mehrnoosh Tashakori, et al.
Publicado: (2022-05-01)

The frequency of <it>NPM1 </it>mutations in childhood acute myeloid leukemia
por: Karamolegou Kalliopi, et al.
Publicado: (2010-10-01)

MiR-424 and miR-155 deregulated expression in cytogenetically normal acute myeloid leukaemia: correlation with NPM1 and FLT3 mutation status
por: Faraoni Isabella, et al.
Publicado: (2012-06-01)

A novel mechanism of NPM1 cytoplasmic localization in acute myeloid leukemia: the recurrent gene fusion NPM1–HAUS1
por: Paulo Vidal Campregher, et al.
Publicado: (2016-07-01)

Late relapse of acute myeloid leukemia with mutated NPM1 after eight years: evidence of NPM1 mutation stability
por: Giovanna Meloni, et al.
Publicado: (2009-02-01)

Low expression of the putative tumour suppressor gene gravin in chronic myeloid leukaemia, myelodysplastic syndromes and acute myeloid leukaemia.
por: Boultwood, J, et al.
Publicado: (2004)

Acute Myeloid Leukaemia with Plasmacytosis
por: Yasmin Akhtar, Saqib Qayyum Ahmad, Shahid Jamal
Publicado: (2016-12-01)

Exploring the acute myeloid leukaemias
por: TB Thapa
Publicado: (2013-10-01)

Acute Myeloid Leukaemia Presenting as Gaze Palsy
por: Evripidis Sykakis, et al.
Publicado: (2011-11-01)

Harnessing the graft-versus-leukaemia effect in acute myeloid leukaemia
por: Sweeney, C
Publicado: (2021)

Isolated Mediastinal Myeloid Sarcoma after NPM1-Positive Pediatric Acute Myeloid Leukemi
por: Özlem Tüfekçi, et al.
Publicado: (2019-11-01)

Acute Myeloid Leukemia with Concomitant BCR-ABL and NPM1 Mutations
por: Benedetta Mariotti, et al.
Publicado: (2019-01-01)

The discovery of <i>NPM1</i> mutations in acute myeloid leukemia
por: Paolo Sportoletti
Publicado: (2020-06-01)

Circular RNAs of the nucleophosmin (NPM1) gene in acute myeloid leukemia
por: Susanne Hirsch, et al.
Publicado: (2017-12-01)

Acute myeloid leukemia with concurrent NPM1 and RUNX1 mutations
por: Zhuang Zuo, et al.
Publicado: (2023-01-01)

Identification of a novel NPM1 mutation in acute myeloid leukemia
por: Yiyi Yao, et al.
Publicado: (2023-10-01)

NPM1 GENETIC VARIANTS: THE IMPORTANCE IN THE DIAGNOSIS OF THE ACUTE MYELOID LEUKEMIA
Publicado: (2023-10-01)

Acute Promyelocytic Leukemia or Acute Myeloid Leukemia with Mutated NPM1?
por: Maximiliano Cloobs Venezia, et al.
Publicado: (2022-11-01)

Clonal evolution patterns in acute myeloid leukemia with NPM1 mutation
por: Sibylle Cocciardi, et al.
Publicado: (2019-05-01)

Secondary acute myeloid leukaemia in children treated for acute lymphoblastic leukaemia.
por: Eden, O, et al.
Publicado: (1998)

Humoral detection of leukaemia-associated antigens in presentation acute myeloid leukaemia.
por: Guinn, B, et al.
Publicado: (2005)

Microarray-based genomic analysis identifies germline and somatic copy number variants and loss of heterozygosity in acute myeloid leukaemia
por: Ambayya @ Ampiah, A Angeli
Publicado: (2015)

Microarray-based genomic analysis identifies germline and somatic copy number variants and loss of heterozygosity in acute myeloid leukaemia
por: Ambayya @ Ampiah, A Angeli, et al.
Publicado: (2018)

ENPP4 and HOXA3 as potential leukaemia stem cell markers in acute myeloid leukaemia
por: Mohd Amin, A, et al.
Publicado: (2023)

Adhesion Deregulation in Acute Myeloid Leukaemia
por: Alicja M. Gruszka, et al.
Publicado: (2019-01-01)

Wnt Signalling in Acute Myeloid Leukaemia
por: Alicja M. Gruszka, et al.
Publicado: (2019-11-01)

Orbital deposit in acute myeloid leukaemia
por: Seal G, et al.
Publicado: (1973-01-01)

Chronic myeloid leukaemia with marked thrombocytosis
por: Jun Ooi, et al.
Publicado: (2021-02-01)

Unprecedented behaviour of chronic myeloid leukaemia
por: Balambika RG, et al.
Publicado: (2016-07-01)

Pitfalls in the molecular follow up of NPM1 mutant acute myeloid leukemia
por: Ulrike Bacher, et al.
Publicado: (2018-10-01)