Secretory phospholipase A2-IID is an effector molecule of CD4+CD25+ regulatory T cells.
Suppression by natural CD4(+)CD25(+) regulatory T cells (Tregs) is one mechanism by which tolerance is maintained. However, the way in which Tregs mediate suppression is not well understood. Here, we show that secreted phospholipase A2 (sPLA2)-IID is selectively produced by Tregs. sPLA2-IID is a pot...
| Main Authors: | , , , , , , , , , , |
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| 格式: | Journal article |
| 语言: | English |
| 出版: |
2009
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