Attenuation of preferential occupancy of 5-HT1A autoreceptors by pindolol in depressed patients: effect of SSRIs or an endophenotype of the depressed state?

Geahča maid

• Preferential 5-HT1A autoreceptor occupancy by pindolol is attenuated in depressed patients: effect of treatment or an endophenotype of depression?
  Dahkki: Rabiner, E, et al.
  Almmustuhtton: (2004)
• Electrophysiological and neurochemical evidence that pindolol has agonist properties at the 5-HT1A autoreceptor in vivo.
  Dahkki: Clifford, E, et al.
  Almmustuhtton: (1998)
• Drug action at the 5-HT(1A) receptor in vivo: autoreceptor and postsynaptic receptor occupancy examined with PET and [carbonyl-(11)C]WAY-100635.
  Dahkki: Rabiner, E, et al.
  Almmustuhtton: (2000)
• SSRIs versus other antidepressants for depressive disorder.
  Dahkki: Geddes, J, et al.
  Almmustuhtton: (2000)
• Systematic review of pindolol augmentation of serotonergic antidepressant treatment for major depressive disorder
  Dahkki: Whale, R, et al.
  Almmustuhtton: (2005)