Genetic variants associated with Lp(a) lipoprotein level and coronary disease.

Genetic variants associated with Lp(a) lipoprotein level and coronary disease.

BACKGROUND: An increased level of Lp(a) lipoprotein has been identified as a risk factor for coronary artery disease that is highly heritable. The genetic determinants of the Lp(a) lipoprotein level and their relevance for the risk of coronary disease are incompletely understood. METHODS: We used a...

Full description

Bibliographic Details
Main Authors:	Clarke, R, Peden, J, Hopewell, J, Kyriakou, T, Goel, A, Heath, S, Parish, S, Barlera, S, Franzosi, MG, Rust, S, Bennett, D, Silveira, A, Malarstig, A, Green, F, Lathrop, M, Gigante, B, Leander, K, de Faire, U, Seedorf, U, Hamsten, A, Collins, R, Watkins, H, Farrall, M
Format:	Journal article
Language:	English
Published:	2009

Similar Items

COMMON GENETIC VARIANTS ASSOCIATED WITH LOW Lp(a) KRINGLE-IV COPY NUMBER, HIGH Lp(a) CONCENTRATION, AND INCREASED RISK OF CORONARY HEART DISEASE
by: Seedorf, U, et al.
Published: (2010)

Common Genetic Variants Associated With Higher Lp(a) Concentrations and Increased Risk of Coronary Heart Disease
by: Clarke, R, et al.
Published: (2009)

ASSOCIATION STUDY OF CORONARY ARTERY DISEASE (CAD) USING HUMANCVD 50K CHIP
by: Goel, A, et al.
Published: (2009)

Impact of lipoprotein(a) levels and apolipoprotein(a) isoform size on risk of coronary heart disease.
by: Hopewell, J, et al.
Published: (2014)

Impact of lipoprotein(a) levels and apolipoprotein(a) isoform size on risk of coronary heart disease
by: Hopewell, J, et al.
Published: (2014)

LPA NULL MUTATION GENOTYPING AND QPCR ANALYSIS REFINE KRINGLE ISOFORM ANALYSIS OF LP(A) LEVELS
by: Kyriakou, T, et al.
Published: (2014)

A common LPA null allele associates with lower lipoprotein(a) levels and coronary artery disease risk
by: Kyriakou, T, et al.
Published: (2014)

A common LPA null allele associates with lower lipoprotein(a) levels and coronary artery disease risk.
by: Kyriakou, T, et al.
Published: (2014)

Multiple QTL influence the serum Lp(a) concentration: a genome-wide linkage screen in the PROCARDIS study.
by: Barlera, S, et al.
Published: (2007)

Association of Apolipoprotein(a) Isoforms With Coronary Heart Disease is Mediated Through Plasma Lipoprotein(a) Levels
by: Hopewell, J, et al.
Published: (2010)

Multiple QTL influence the serum Lp(a) concentration: A genome-wide linkage screen in the PROCARDIS study
by: Barlera, et al.
Published: (2007)

Independent relevance of renal function for coronary artery disease
by: Hopewell, J, et al.
Published: (2010)

Genetic Variants in Lp(a) Lipoprotein and Coronary Disease REPLY
by: Farrall, M, et al.
Published: (2010)

Susceptibility to coronary artery disease and diabetes is encoded by distinct, tightly linked SNPs in the ANRIL locus on chromosome 9p
by: Broadbent, H, et al.
Published: (2008)

Susceptibility to coronary artery disease and diabetes is encoded by distinct, tightly linked SNPs in the ANRIL locus on chromosome 9p.
by: Broadbent, H, et al.
Published: (2008)

Identification of ZNF366 and PTPRD as novel determinants of plasma homocysteine in a family-based genome-wide association study.
by: Mälarstig, A, et al.
Published: (2009)

Lipoprotein a - Lp(a)
by: Tapan Ghose
Published: (2024-03-01)

Oxidized phospholipids, Lp(a) and coronary heart disease risk
by: Clarke, R, et al.
Published: (2012)

Relationship between CAD risk genotype in the chromosome 9p21 locus and gene expression. Identification of eight new ANRIL splice variants.
by: Folkersen, L, et al.
Published: (2009)

Remnant lipoproteins are related to intima-media thickness of the carotid artery independently of LDL cholesterol and plasma triglycerides.
by: Karpe, F, et al.
Published: (2001)

Treatment effects on serum lipoprotein lipids, apolipoproteins and low density lipoprotein particle size and relationships of lipoprotein variables to progression of coronary artery disease in the Bezafibrate Coronary Atherosclerosis Intervention Trial (BECAIT).
by: Ruotolo, G, et al.
Published: (1998)

Quantitative trait genetic linkage analysis of body mass index in familial coronary artery disease.
by: Specchia, C, et al.
Published: (2008)

Postprandial enrichment of remnant lipoproteins with apoC-I in healthy normolipidemic men with early asymptomatic atherosclerosis.
by: Björkegren, J, et al.
Published: (2002)

Alimentary lipemia, postprandial triglyceride-rich lipoproteins, and common carotid intima-media thickness in healthy, middle-aged men.
by: Boquist, S, et al.
Published: (1999)

Novel associations of CPS1, MUT, NOX4, and DPEP1 with plasma homocysteine in a healthy population: a genome-wide evaluation of 13 974 participants in the Women's Genome Health Study.
by: Paré, G, et al.
Published: (2009)

USE OF ENCODE DATA TO IDENTIFY PUTATIVE FUNCTIONAL VARIANTS IN CORONARY ARTERY DISEASE GWAS
by: Goel, A, et al.
Published: (2014)

Lipoprotein(a) genetic variants associated with coronary and peripheral vascular disease but not with stroke risk in the Heart Protection Study.
by: Hopewell, J, et al.
Published: (2011)

Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.
by: Chasman, D, et al.
Published: (2009)

Postprandial lipoprotein metabolism and atherosclerosis.
by: Karpe, F, et al.
Published: (1995)

A Genome-Wide Association Study of Risk of Coronary Artery Disease in European and South Asian Populations
by: Hopewell, J, et al.
Published: (2010)

INSULIN, LIPOPROTEINS AND HEMOSTATIC FUNCTION
by: Hamsten, A, et al.
Published: (1995)

Genome-wide mapping of susceptibility to coronary artery disease identifies a novel replicated locus on chromosome 17.
by: Farrall, M, et al.
Published: (2006)

Genome-wide mapping of susceptibility to coronary artery disease identifies a novel replicated locus on Chromosome 17
by: Farrall, M, et al.
Published: (2006)

Genome-wide mapping of susceptibility to coronary artery disease identifies a novel replicated locus on chromosome 17.
by: Farrall, M, et al.
Published: (2006)

Human intestinal alkaline phosphatase--release to the blood is linked to lipid absorption, but removal from the blood is not linked to lipoprotein clearance.
by: Domar, U, et al.
Published: (1993)

REMNANT LIPOPROTEINS AND CORONARY ARTERY DISEASE PROGRESSION
by: Karpe, F, et al.
Published: (1995)

Lipoprotein associated phospholipase A2 (Lp-PLA2) and long-term prognosis after TIA and stroke
by: Segal, H, et al.
Published: (2013)

Remnants of postprandial triglyceride-rich lipoproteins and atherosclerosis
by: Karpe, F, et al.
Published: (1999)

Lipoprotein(a) and multi-stage atherogenesis: coronary atherosclerosis, cerebrovascular complications and other correlations of Lp(a) and apo(a)
by: A. V. Tikhonov, et al.
Published: (2010-06-01)

Composition of human low density lipoprotein: effects of postprandial triglyceride-rich lipoproteins, lipoprotein lipase, hepatic lipase and cholesteryl ester transfer protein.
by: Karpe, F, et al.
Published: (1993)