Pathway level subtyping identifies a slow-cycling biological phenotype associated with poor clinical outcomes in colorectal cancer

Pathway level subtyping identifies a slow-cycling biological phenotype associated with poor clinical outcomes in colorectal cancer

Molecular stratification using gene-level transcriptional data has identified subtypes with distinctive genotypic and phenotypic traits, as exemplified by the consensus molecular subtypes (CMS) in colorectal cancer (CRC). Here, rather than gene-level data, we make use of gene ontology and biological...

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Hlavní autoři: Malla, SB, Byrne, RM, Lafarge, MW, Corry, SM, Fisher, NC, Tsantoulis, PK, Mills, ML, Ridgway, RA, Lannagan, TRM, Najumudeen, AK, Gilroy, KL, Amirkhah, R, Maguire, SL, Mulholland, EJ, Belnoue-Davis, HL, Grassi, E, Viviani, M, Rogan, E, Redmond, KL, Sakhnevych, S, McCooey, AJ, Bull, C, Hoey, E, Sinevici, N, Domingo, E, Blake, A, Maughan, TS, Leedham, SJ, Koelzer, VH
Médium: Journal article
Jazyk:English
Vydáno: Nature Research 2024

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