Cell-surface expression and immune receptor recognition of HLA-B27 homodimers.

Cell-surface expression and immune receptor recognition of HLA-B27 homodimers.

OBJECTIVE: HLA-B27 is capable of forming in vitro a heavy-chain homodimer structure lacking beta(2)-microglobulin. We undertook this study to ascertain if patients with spondylarthritis express beta(2)-microglobulin-free HLA-B27 heavy chains in the form of homodimers and receptors for HLA-B27 homod...

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Bibliografiske detaljer
Main Authors:	Kollnberger, S, Bird, L, Sun, M, Retiere, C, Braud, V, McMichael, A, Bowness, P
Format:	Journal article
Sprog:	English
Udgivet:	2002

Lignende værker

Identification and characterisation of cell surface HLA-B27 homodimers
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Udgivet: (2002)

HLA-B27 transgenic rodents express cell surface HLA-B27 heavy chain homodimers and multimers.
af: Bowness, P, et al.
Udgivet: (2003)

Lymphoblastoid cells express HLA-B27 homodimers both intracellularly and at the cell surface following endosomal recycling.
af: Bird, L, et al.
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HLA-B27 heavy chain homodimers are expressed in HLA-B27 transgenic rodent models of spondyloarthritis and are ligands for paired Ig-like receptors.
af: Kollnberger, S, et al.
Udgivet: (2004)

CELL SURFACE EXPRESSION OF HLA B27 HEAVY CHAINS AND SPECIFIC RECOGNITION BY IMMUNE RECEPTORS, POSSIBLE ROLE IN SPONDYLOARTHROPATHY
af: Kollnberger, S, et al.
Udgivet: (2002)

TARGETING MONOCYTE-EXPRESSED HLA-B27 HOMODIMERS IN ANKYLOSING SPONDYLITIS
af: Bowness, P, et al.
Udgivet: (2010)

TARGETING MONOCYTE-EXPRESSED HLA-B27 HOMODIMERS IN ANKYLOSING SPONDYLITIS
af: Bowness, P, et al.
Udgivet: (2010)

The pathogenesis of spondyloarthritides - HLA-B-27 homodimer expression on human monocyte/macrophage cell lines
af: McHugh, K, et al.
Udgivet: (2008)

The role of cell surface HLA-B27 heavy chain homodimer interactions with NK receptors in the pathogenesis of spondyloarthritis
af: Kollnberger, S
Udgivet: (2005)

Inhibiting HLA-B27 homodimer-driven immune cell inflammation in spondylarthritis.
af: Payeli, S, et al.
Udgivet: (2012)

HLA-B-27 heavy chain homodimer formation and natural killer cell family interaction - comparison of two HLA-B-27 subtypes in vitro
af: Giles, J, et al.
Udgivet: (2008)

Interaction of HLA-B27 homodimers with KIR3DL1 and KIR3DL2, unlike HLA-B27 heterotrimers, is independent of the sequence of bound peptide.
af: Kollnberger, S, et al.
Udgivet: (2007)

Th17 cells expressing KIR3DL2+ and responsive to HLA-B27 homodimers are increased in ankylosing spondylitis.
af: Bowness, P, et al.
Udgivet: (2011)

Dimers are forever. Expression and recognition of abnormal HLA-B27 in spondylo arthritis
af: Bowness, P, et al.
Udgivet: (2005)

HLA-B27 FORMS HEAVY CHAIN HOMODIMERS IN VITRO AND IN VIVO THAT BIND TO CELLULAR RECEPTORS INCLUDING LILR AND KIR FAMILY MEMBERS
af: McHugh, K, et al.
Udgivet: (2010)

HLA B27 can form heavy chain homodimers in vivo and in vivo, possible role of cys 67.
af: Bowness, P, et al.
Udgivet: (1998)

HLA-B27-Homodimer-Specific Antibody Modulates the Expansion of Pro-Inflammatory T-Cells in HLA-B27 Transgenic Rats.
af: Osiris Marroquin Belaunzaran, et al.
Udgivet: (2015-01-01)

Functional characterisation of HLA-B27 in autoimmunity
af: Kollnberger, S, et al.
Udgivet: (2001)

HLA-B27 homodimers differ in their interactions with LILRB1, LILRB2, KIR3DL1 and KIR3DL2 compared to HLA-B27 heterotrimers
af: Giles, J, et al.
Udgivet: (2010)

HLA-B*2709, A SUBTYPE NOT ASSOCIATED WITH ANKYLOSING SPONDYLITIS, FORMS FEWER HOMODIMERS THAN HLA-B*2705
af: Giles, J, et al.
Udgivet: (2010)

HLA-B27 homodimers and free H chains are stronger ligands for leukocyte Ig-like receptor B2 than classical HLA class I.
af: Giles, J, et al.
Udgivet: (2012)

Cutting edge: HLA-B27 can form a novel beta 2-microglobulin-free heavy chain homodimer structure.
af: Allen, R, et al.
Udgivet: (1999)

Identification of T cell receptor recognition residues for a viral peptide presented by HLA B27.
af: Bowness, P, et al.
Udgivet: (1994)

IDENTIFICATION OF T-CELL RECEPTOR RECOGNITION RESIDUES FOR AN INFLUENZA-VIRUS NONAMER PEPTIDE EPITOPE PRESENTED BY HLA B27
af: Bowness, P, et al.
Udgivet: (1995)

EXPRESSION OF HLA-B27 HEAVY CHAIN FORMS IN ANKYLOSING SPONDYLITIS AND HLA-B27 POSITIVE CELL LINES
af: Rysnik, O, et al.
Udgivet: (2012)

The KIRs of HLA-B27: the role of HLA-B27 KIR interactions in infection and spondyloarthritis
af: Wong-Baeza, I, et al.
Udgivet: (2011)

Residue Cys-67 of HLA-B27 contributes to antigen presentation and T cell recognition of HLA-B27 restricted T cell epitopes.
af: Appel, H, et al.
Udgivet: (2004)

The role of B27 heavy chain dimer immune receptor interactions in spondyloarthritis.
af: Kollnberger, S, et al.
Udgivet: (2009)

The role of HLA-B27 interactions with natural killer receptors in the pathogenesis of spondyloarthritis
af: Kollnberger, S, et al.
Udgivet: (2007)

The solvent-inaccessible Cys67 residue of HLA-B27 contributes to T cell recognition of HLA-B27/peptide complexes.
af: Appel, H, et al.
Udgivet: (2004)

The role of HLA-B27 in spondyloarthritis.
af: Allen, R, et al.
Udgivet: (1999)

Factors determining the cell surface expression of a novel HLA-B27 epitope
af: McHugh, K, et al.
Udgivet: (2010)

HLA-B27 HEAVY CHAIN DIMER EXPRESSION IN SPONDYLOARTHRITIS
af: Rysnik, O, et al.
Udgivet: (2012)

HLA-B27
af: Bowness, P
Udgivet: (2015)

HLA-B27: natural function and pathogenic role in spondyloarthritis.
af: McMichael, A, et al.
Udgivet: (2002)

Expression of aberrant HLA-B27 molecules is dependent on B27 dosage and peptide supply.
af: McHugh, K, et al.
Udgivet: (2014)

Direct visualisation of HLA-B27 forms in cell lines and Spondyloarthropathy tissues
af: Rysnik, O, et al.
Udgivet: (2013)

THE ARTHRITIS-ASSOCIATED HLA-B(star)27:05 FORMS MORE CELL SURFACE B27 DIMER AND FREE HEAVY CHAIN LIGANDS FOR KIR3DL2 AND LILRB2 IMMUNORECEPTORS THAN HLA(star)B27:09
af: Shaw, J, et al.
Udgivet: (2013)

Molecular Characterisation Of The Killer Cell Immunoglobulin-Like Receptor 3DL2 Binding To Aberrant HLA-B27 Heavy Chains In Spondyloarthritis
af: Hatano, H, et al.
Udgivet: (2013)

Importance of a conserved TCR J alpha-encoded tyrosine for T cell recognition of an HLA B27/peptide complex.
af: Bowness, P, et al.
Udgivet: (1998)