The basic helix-loop-helix transcription factor SHARP1 is an oncogenic driver in MLL-AF6 acute myelogenous leukemia

The basic helix-loop-helix transcription factor SHARP1 is an oncogenic driver in MLL-AF6 acute myelogenous leukemia

Acute Myeloid Leukemia (AML) with MLL gene rearrangements demonstrate unique gene expression profiles driven by MLL-fusion proteins. Here, we identify the circadian clock transcription factor SHARP1 as a novel oncogenic target in MLL-AF6 AML, which has the worst prognosis among all subtypes of MLL-r...

Bibliografske podrobnosti
Main Authors:	Numata, A, Kwok, HS, Kawasaki, A, Li, J, Zhou, Q-L, Kerry, J, Benoukraf, T, Bararia, D, Li, F, Ballabio, E, Tapia, M, Deshpande, AJ, Welner, RS, Delwel, R, Yang, H, Milne, TA, Taneja, R, Tenen, DG
Format:	Journal article
Jezik:	English
Izdano:	Springer Nature 2018

Podobne knjige/članki

The basic helix-loop-helix transcription factor SHARP1 is an oncogenic driver in MLL-AF6 acute myelogenous leukemia
od: Akihiko Numata, et al.
Izdano: (2018-04-01)

Molecular and Epigenetic Mechanisms of MLL in Human Leukemogenesis.
od: Ballabio, E, et al.
Izdano: (2012)

Helix-helix interactions in membrane proteins: coarse-grained simulations of glycophorin a helix dimerization.
od: Psachoulia, E, et al.
Izdano: (2008)

Molecular dissection of SCL helix-loop-helix domain.
od: Schlaeger, T, et al.
Izdano: (2003)

The Evolution of the Neural Basic Helix-Loop-Helix Proteins
od: Michel Vervoort, et al.
Izdano: (2001-01-01)

Helix-Loop-Helix Proteins in Adaptive Immune Development
od: Megan Aubrey, et al.
Izdano: (2022-05-01)

THE DOUBLE HELIX /
od: Trueit, Trudi Strain, author 655686
Izdano: (2020)

Origin and diversification of basic-helix-loop-helix proteins in plants.
od: Pires, N, et al.
Izdano: (2010)

The role of extra-membranous inter-helical loops in helix-helix interactions.
od: Ulmschneider, M, et al.
Izdano: (2005)

Transmembrane helix-helix interactions: comparative simulations of the glycophorin a dimer.
od: Cuthbertson, J, et al.
Izdano: (2006)

A Classification of Basic Helix-Loop-Helix Transcription Factors of Soybean
od: Karen A. Hudson, et al.
Izdano: (2015-01-01)

The accessory helix of complexin functions by stabilizing central helix secondary structure
od: Daniel T Radoff, et al.
Izdano: (2014-11-01)

Polar/Ionizable residues in transmembrane segments: effects on helix-helix packing.
od: Manuel Bañó-Polo, et al.
Izdano: (2012-01-01)

The path to the double helix/
od: 234301 Olby, Robert
Izdano: (1974)

The impossibility of the triple helix
od: David Emanuel Andersson, et al.
Izdano: (2020-08-01)

Structural studies on the basic-helix-loop-helix region from MyoD
od: Ma, Philip Chun-Ming
Izdano: (2005)

Framed general helix and framed ζ3-slant helix in ℝ4
od: Ateş Mine, et al.
Izdano: (2023-09-01)

An exploration of alternative visualisations of the basic helix-loop-helix protein interaction network
od: Amoutzias Grigoris D, et al.
Izdano: (2007-08-01)

Genome-wide analysis of basic helix-loop-helix superfamily members in peach.
od: Chunhua Zhang, et al.
Izdano: (2018-01-01)

HEXA HELIX: KOLABORASI QUADRUPLE HELIX DAN QUINTUPLE HELIX INNOVATION SEBAGAI SOLUSI UNTUK PEMULIHAN EKONOMI PASCA COVID-19
od: Deri Firmansyah, et al.
Izdano: (2022-12-01)

The human leukemic oncogene MLL-AF4 promotes hyperplastic growth of hematopoietic tissues in Drosophila larvae
od: Julie A. Johannessen, et al.
Izdano: (2023-10-01)

Unraveling the Activation Mechanism of Taspase1 which Controls the Oncogenic AF4–MLL Fusion Protein
od: Samaneh Sabiani, et al.
Izdano: (2015-05-01)

Lamprey neural Helix-Loop-Helix (HLH) genes and the evolution of the vertebrate nervous system
od: Lara-Ramirez, R
Izdano: (2013)

Neofunctionalisation of basic helix-loop-helix proteins occurred when embryophytes colonised the land
od: Bonnot, C, et al.
Izdano: (2019)

Interactions of a transmembrane helix and a membrane: Comparative simulations of bacteriorhodopsin helix A
od: Ulmschneider, M, et al.
Izdano: (2004)

Balancing force field protein-lipid interactions to capture transmembrane helix-helix association
od: Domański, J, et al.
Izdano: (2018)

On the path to extinction: Helix godetiana Kobelt, 1878, the only threatened Helix species in Greece
od: Leonidas Maroulis, et al.
Izdano: (2025-01-01)

Promoterless Luciferase Reporter Gene Is Transactivated by Basic Helix-Loop-Helix Transcription Factors
od: Seok Jong Hong, et al.
Izdano: (2002-12-01)

Bio-inspired swimming helix
od: Johnson, Benjamin C. F. (Benjamin Cedar Fruehauf)
Izdano: (2013)

Transmembrane helix : simple or complex
od: Wong, Wing-Cheong, et al.
Izdano: (2013)

STAFFING MECHANISM TRIPLE HELIX
od: L. Artamonova, et al.
Izdano: (2016-06-01)

Exo-chirality of the α-helix
od: Jose M. Martínez-Parra, et al.
Izdano: (2024-08-01)

The Double Helix of Data Extraction
od: Sebastián Lehuedé
Izdano: (2024-03-01)

Triple Helix Inovasi Pemerintahan
od: Pratiwi Pratiwi
Izdano: (2020-03-01)

Questions about the HELIX trial
od: Deepika Kainth, et al.
Izdano: (2021-12-01)

STAFFING MECHANISM TRIPLE HELIX
od: L. Artamonova, et al.
Izdano: (2019-02-01)

An unusual cystic lesion on the helix
od: Megha B.S. Patel, et al.
Izdano: (2014-01-01)

Helix capping in RNA structure.
od: Jung C Lee, et al.
Izdano: (2014-01-01)

Helix-Hopes on Finite Hyperfields
od: Thomas Vougiouklis, et al.
Izdano: (2016-12-01)

Questions about the HELIX trial
od: Karoline Aker, et al.
Izdano: (2021-12-01)