Altered desaturation and elongation of fatty acids in hormone-sensitive lipase null mice.

BACKGROUND: Hormone-sensitive lipase (HSL) is expressed predominantly in adipose tissue, where it plays an important role in catecholamine-stimulated hydrolysis of stored lipids, thus mobilizing fatty acids. HSL exhibits broad substrate specificity and besides acylglycerides it hydrolyzes cholester...

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Détails bibliographiques
Auteurs principaux: Fernandez, C, Schuhmann, K, Herzog, R, Fielding, B, Frayn, K, Shevchenko, A, James, P, Holm, C, Ström, K
Format: Journal article
Langue:English
Publié: 2011