Structural insight into BLM recognition by TopBP1
Topoisomerase IIβ binding protein 1 (TopBP1) is a critical protein-protein interaction hub in DNA replication checkpoint control. It was proposed that TopBP1 BRCT5 interacts with Bloom syndrome helicase (BLM) to regulate genome stability through either phospho-Ser304 or phospho-Ser338 of BLM. Here w...
المؤلفون الرئيسيون: | Sun, L, Huang, Y, Edwards, R, Yang, S, Blackford, A, Niedzwiedz, W, Glover, J |
---|---|
التنسيق: | Journal article |
اللغة: | English |
منشور في: |
Elsevier
2017
|
مواد مشابهة
-
Understanding the role of the TOPBP1 and BLM interaction in promoting genome stability
حسب: Smethurst, E
منشور في: (2017) -
Spatial organization and functions of Chk1 activation by TopBP1 biomolecular condensates
حسب: Tom Egger, وآخرون
منشور في: (2024-04-01) -
TopBP1 Governs Hematopoietic Stem/Progenitor Cells Survival in Zebrafish Definitive Hematopoiesis.
حسب: Lei Gao, وآخرون
منشور في: (2015-07-01) -
TopBP1 utilises a bipartite GINS binding mode to support genome replication
حسب: Matthew Day, وآخرون
منشور في: (2024-02-01) -
TopBP1 contributes to the chemoresistance in non-small cell lung cancer through upregulation of p53
حسب: Lv Y, وآخرون
منشور في: (2016-09-01)