Structural insight into BLM recognition by TopBP1

Structural insight into BLM recognition by TopBP1

Topoisomerase IIβ binding protein 1 (TopBP1) is a critical protein-protein interaction hub in DNA replication checkpoint control. It was proposed that TopBP1 BRCT5 interacts with Bloom syndrome helicase (BLM) to regulate genome stability through either phospho-Ser304 or phospho-Ser338 of BLM. Here w...

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Үндсэн зохиолчид:	Sun, L, Huang, Y, Edwards, R, Yang, S, Blackford, A, Niedzwiedz, W, Glover, J
Формат:	Journal article
Хэл сонгох:	English
Хэвлэсэн:	Elsevier 2017

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