Fission yeast Cdc23/Mcm10 functions after pre-replicative complex formation to promote Cdc45 chromatin binding.

Using a cytological assay to monitor the successive chromatin association of replication proteins leading to replication initiation, we have investigated the function of fission yeast Cdc23/Mcm10 in DNA replication. Inactivation of Cdc23 before replication initiation using tight degron mutations has...

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Bibliographic Details
Main Authors: Gregan, J, Lindner, K, Brimage, L, Franklin, R, Namdar, M, Hart, E, Aves, S, Kearsey, S
Format: Journal article
Language:English
Published: 2003