Inflammatory disease status and response to TNF blockade are associated with mechanisms of endotoxin tolerance
The mechanisms of endotoxin tolerance (ET), which down-regulate inflammation, are well described in response to exogenous toll-like receptor ligands, but few studies have focused on ET-associated mechanisms in inflammatory disease. As blocking TNF can attenuate the development of ET, the effect of a...
Main Authors: | Taylor, PC, Clanchy, FIL, Borghese, F, Bystrom, J, Balog, A, Penn, H, Hull, DN, Williams, RO, Mageed, RA |
---|---|
Format: | Journal article |
Language: | English |
Published: |
Elsevier
2024
|
Similar Items
-
Disease status in human and experimental arthritis, and response to TNF blockade, is associated with MHC class II invariant chain (CD74) isoform expression
by: Clanchy, FIL, et al.
Published: (2022) -
TLR expression profiles are a function of disease status in rheumatoid arthritis and experimental arthritis
by: Clanchy, FIL, et al.
Published: (2021) -
TNFα inhibitors reduce bone loss in rheumatoid arthritis independent of clinical response by reducing osteoclast precursors and IL-20
by: Al-Bogami, M, et al.
Published: (2020) -
Incomplete response of inflammatory arthritis to TNF alpha blockade is associated with the Th17 pathway
by: Alzabin, S, et al.
Published: (2012) -
Incomplete response of inflammatory arthritis to TNFα blockade is associated with the Th17 pathway.
by: Alzabin, S, et al.
Published: (2012)