Inflammatory disease status and response to TNF blockade are associated with mechanisms of endotoxin tolerance

The mechanisms of endotoxin tolerance (ET), which down-regulate inflammation, are well described in response to exogenous toll-like receptor ligands, but few studies have focused on ET-associated mechanisms in inflammatory disease. As blocking TNF can attenuate the development of ET, the effect of a...

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Những tác giả chính: Taylor, PC, Clanchy, FIL, Borghese, F, Bystrom, J, Balog, A, Penn, H, Hull, DN, Williams, RO, Mageed, RA
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: Elsevier 2024