Immunodiagnosis of snake bite.
Management of a patient with snake bite is influenced by the nature of the offending snake. Species diagnosis based on the patient's history and physical signs is often unreliable and the possibility of making a species diagnosis by immunological means has therefore been investigated. Wound asp...
| Main Authors: | , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
1974
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| _version_ | 1797083867326185472 |
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| author | Greenwood, B Warrell, D Davidson, N Ormerod, L Reid, H |
| author_facet | Greenwood, B Warrell, D Davidson, N Ormerod, L Reid, H |
| author_sort | Greenwood, B |
| collection | OXFORD |
| description | Management of a patient with snake bite is influenced by the nature of the offending snake. Species diagnosis based on the patient's history and physical signs is often unreliable and the possibility of making a species diagnosis by immunological means has therefore been investigated. Wound aspirates, blister fluids, sera, and urine samples from patients with snake bite were examined for the presence of species-specific venoms using immunodiffusion. A positive species diagnosis was made in 40 out of 101 patients. Immunodiagnosis was especially successful in patients bitten by the puff adder, Bitis arietans, and the African spitting cobra, Naja nigricollis. A higher success rate could probably be achieved using more specific antisera and more sensitive assay techniques. |
| first_indexed | 2024-03-07T01:47:33Z |
| format | Journal article |
| id | oxford-uuid:98f1e167-19b0-4e45-b968-3ecab9fafede |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T01:47:33Z |
| publishDate | 1974 |
| record_format | dspace |
| spelling | oxford-uuid:98f1e167-19b0-4e45-b968-3ecab9fafede2022-03-27T00:10:39ZImmunodiagnosis of snake bite.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:98f1e167-19b0-4e45-b968-3ecab9fafedeEnglishSymplectic Elements at Oxford1974Greenwood, BWarrell, DDavidson, NOrmerod, LReid, HManagement of a patient with snake bite is influenced by the nature of the offending snake. Species diagnosis based on the patient's history and physical signs is often unreliable and the possibility of making a species diagnosis by immunological means has therefore been investigated. Wound aspirates, blister fluids, sera, and urine samples from patients with snake bite were examined for the presence of species-specific venoms using immunodiffusion. A positive species diagnosis was made in 40 out of 101 patients. Immunodiagnosis was especially successful in patients bitten by the puff adder, Bitis arietans, and the African spitting cobra, Naja nigricollis. A higher success rate could probably be achieved using more specific antisera and more sensitive assay techniques. |
| spellingShingle | Greenwood, B Warrell, D Davidson, N Ormerod, L Reid, H Immunodiagnosis of snake bite. |
| title | Immunodiagnosis of snake bite. |
| title_full | Immunodiagnosis of snake bite. |
| title_fullStr | Immunodiagnosis of snake bite. |
| title_full_unstemmed | Immunodiagnosis of snake bite. |
| title_short | Immunodiagnosis of snake bite. |
| title_sort | immunodiagnosis of snake bite |
| work_keys_str_mv | AT greenwoodb immunodiagnosisofsnakebite AT warrelld immunodiagnosisofsnakebite AT davidsonn immunodiagnosisofsnakebite AT ormerodl immunodiagnosisofsnakebite AT reidh immunodiagnosisofsnakebite |