Domain-specific interactions of talin with the membrane-proximal region of the integrin beta3 subunit.

Domain-specific interactions of talin with the membrane-proximal region of the integrin beta3 subunit.

Activation (affinity regulation) of integrin adhesion receptors controls cell migration and extracellular matrix assembly. Talin connects integrins with actin filaments and influences integrin affinity by binding to the integrins' short cytoplasmic beta-tail. The principal beta-tail binding sit...

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Bibliografiske detaljer
Main Authors:	Ulmer, T, Calderwood, D, Ginsberg, M, Campbell, I
Format:	Journal article
Sprog:	English
Udgivet:	2003

Lignende værker

Structural determinants of integrin recognition by talin.
af: García-Alvarez, B, et al.
Udgivet: (2003)

The talin-tail interaction places integrin activation on FERM ground.
af: Campbell, I, et al.
Udgivet: (2004)

Beta integrin tyrosine phosphorylation is a conserved mechanism for regulating talin-induced integrin activation.
af: Anthis, N, et al.
Udgivet: (2009)

Structural basis of integrin activation by talin.
af: Wegener, K, et al.
Udgivet: (2007)

Structural diversity in integrin/talin interactions.
af: Anthis, N, et al.
Udgivet: (2010)

The molecular basis of filamin binding to integrins and competition with talin.
af: Kiema, T, et al.
Udgivet: (2006)

An integrin phosphorylation switch: the effect of beta3 integrin tail phosphorylation on Dok1 and talin binding.
af: Oxley, C, et al.
Udgivet: (2008)

The talin head domain reinforces integrin-mediated adhesion by promoting adhesion complex stability and clustering.
af: Stephanie J Ellis, et al.
Udgivet: (2014-11-01)

A membrane-distal segment of the integrin alpha IIb cytoplasmic domain regulates integrin activation.
af: Ginsberg, M, et al.
Udgivet: (2001)

The Connection Between Rap1 and Talin1 in the Activation of Integrins in Blood Cells
af: Hao Sun, et al.
Udgivet: (2022-06-01)

The structure of an integrin/talin complex reveals the basis of inside-out signal transduction.
af: Anthis, N, et al.
Udgivet: (2009)

Conformational changes in talin on binding to anionic phospholipid membranes facilitate signaling by integrin transmembrane helices.
af: Antreas C Kalli, et al.
Udgivet: (2013-10-01)

Computational studies of talin-mediated integrin activation
af: Kalli, A
Udgivet: (2013)

The talin FERM domain is not so FERM
af: Campbell, I
Udgivet: (2010)

Mechanism of integrin activation by talin and its cooperation with kindlin
af: Fan Lu, et al.
Udgivet: (2022-04-01)

NMR analysis of structure and dynamics of the cytosolic tails of integrin alpha IIb beta 3 in aqueous solution.
af: Ulmer, T, et al.
Udgivet: (2001)

Talin and kindlin : batman and robin of Mac1 integrin activation?
af: Henni Djunaidi.
Udgivet: (2009)

The structure of the talin/integrin complex at a lipid bilayer: an NMR and MD simulation study.
af: Kalli, A, et al.
Udgivet: (2010)

Structural basis of the migfilin-filamin interaction and competition with integrin beta tails.
af: Lad, Y, et al.
Udgivet: (2008)

Nanoscopy reveals integrin clustering reliant on kindlin-3 but not talin-1
af: Yuanyuan Wu, et al.
Udgivet: (2025-01-01)

Integrin activating molecule-talin1 promotes skin fibrosis in systemic sclerosis
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Udgivet: (2024-05-01)

Mechanotransduction in talin through the interaction of the R8 domain with DLC1.
af: Alexander William M Haining, et al.
Udgivet: (2018-07-01)

Investigating the roles of cytoplasmic proteins talin and kindlin3 in integrin LFA-1 activation
af: Li, Yan Feng
Udgivet: (2011)

A computational analysis of the dynamic roles of talin, Dok1, and PIPKI for integrin activation.
af: Florian Geier, et al.
Udgivet: (2011-01-01)

The Collagen Receptor Discoidin Domain Receptor 1b Enhances Integrin β1-Mediated Cell Migration by Interacting With Talin and Promoting Rac1 Activation
af: Corina M. Borza, et al.
Udgivet: (2022-03-01)

Integrin subunit beta 8 contributes to lenvatinib resistance in HCC
af: Wei Hou, et al.
Udgivet: (2022-07-01)

Structural basis for the interaction between the cytoplasmic domain of the hyaluronate receptor layilin and the talin F3 subdomain.
af: Wegener, K, et al.
Udgivet: (2008)

Kindlin-2 cooperates with talin to activate integrins and induces cell spreading by directly binding paxillin
af: Marina Theodosiou, et al.
Udgivet: (2016-01-01)

Structure of Rap1b bound to talin reveals a pathway for triggering integrin activation
af: Liang Zhu, et al.
Udgivet: (2017-11-01)

Paxillin: A Hub for Mechano-Transduction from the β3 Integrin-Talin-Kindlin Axis
af: Marta Ripamonti, et al.
Udgivet: (2022-04-01)

Functional characterization of the trans-membrane domain interactions of the Sec61 protein translocation complex beta-subunit
af: Zhao Xueqiang, et al.
Udgivet: (2009-10-01)

Interaction Analyses of the Integrin β2 Cytoplasmic Tail with the F3 FERM Domain of Talin and 14-3-3ζ Reveal a Ternary Complex with Phosphorylated Tail
af: Chatterjee, Deepak, et al.
Udgivet: (2017)

THE N-TERMINAL DOMAIN OF TALIN - INITIAL STRUCTURAL AND FUNCTIONAL-STUDIES
af: Rees, D, et al.
Udgivet: (1994)

ITGB (Integrin subunit beta) 3 mutation involved in pulmonary hemorrhage and osteopetrosis
af: Carlos Sendon, et al.
Udgivet: (2019-01-01)

The mechanical response of talin
af: Mingxi Yao, et al.
Udgivet: (2016-07-01)

Structural basis for phosphatidylinositol phosphate kinase type Igamma binding to talin at focal adhesions.
af: de Pereda, J, et al.
Udgivet: (2005)

Quantitative single-protein imaging reveals molecular complex formation of integrin, talin, and kindlin during cell adhesion
af: Lisa S. Fischer, et al.
Udgivet: (2021-02-01)

miRNA-200c-3p targets talin-1 to regulate integrin-mediated cell adhesion
af: Gideon Obeng, et al.
Udgivet: (2021-11-01)

Binding of Rap1 and Riam to Talin1 Fine-Tune β2 Integrin Activity During Leukocyte Trafficking
af: Thomas Bromberger, et al.
Udgivet: (2021-08-01)

Transmembrane and cytoplasmic domains in integrin activation and protein-protein interactions (review).
af: Wegener, K, et al.
Udgivet: (2008)