Asymmetrical dimethylarginine inhibits shear stress-induced nitric oxide release and dilation and elicits superoxide-mediated increase in arteriolar tone.
l-arginine is the substrate used by NO synthase to produce the vasodilator NO. However, in several human diseases, such as hyperhomocysteinemia, diabetes mellitus, and hypertension, there is an increase in serum levels of methylated l-arginines, such as asymmetrical dimethylarginine (ADMA), which ca...
Κύριοι συγγραφείς: | Toth, J, Racz, A, Kaminski, P, Wolin, MS, Bagi, Z, Koller, A |
---|---|
Μορφή: | Journal article |
Γλώσσα: | English |
Έκδοση: |
2007
|
Παρόμοια τεκμήρια
Παρόμοια τεκμήρια
-
Asymmetric dimethylarginine (ADMA) increases the myogenic tone of arterioles due to enhanced release of superoxide
ανά: Toth, J, κ.ά.
Έκδοση: (2007) -
Obesity-induced reduction in nitric oxide-dependent arteriolar dilation in rats. Role of xanthine oxidase-derived superoxide.
ανά: Erdei, N, κ.ά.
Έκδοση: (2006) -
High-fat diet-induced reduction in nitric oxide-dependent arteriolar dilation in rats: role of xanthine oxidase-derived superoxide anion.
ανά: Erdei, N, κ.ά.
Έκδοση: (2006) -
Lack of nitric oxide mediation of flow-dependent arteriolar dilation in type I diabetes is restored by sepiapterin.
ανά: Bagi, Z, κ.ά.
Έκδοση: (2003) -
Hydrogen peroxide modulates arteriolar myogenic tone by activating multiple vasomotor mechanisms
ανά: Cseko, C, κ.ά.
Έκδοση: (2004)