HIV-1 Adaptation to Antigen Processing Results in Population-Level Immune Evasion and Affects Subtype Diversification

HIV-1 Adaptation to Antigen Processing Results in Population-Level Immune Evasion and Affects Subtype Diversification

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The recent HIV-1 vaccine failures highlight the need to better understand virus-host interactions. One key question is why CD8+ Tcell responses to two HIV-Gag regions are uniquely associated with delayed disease progression only in patients expressing a few rare HLA class I variants when these regio...

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Main Authors: Tenzer, S, Crawford, H, Pymm, P, Gifford, R, Sreenu, V, Weimershaus, M, deOliveira, T, Burgevin, A, Gerstoft, J, Akkad, N, Lunn, D, Fugger, L, Bell, J, Schild, H, vanEndert, P, Iversen, A
格式: Journal article
出版: 2014

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