Human deficiencies of fucosylation and sialylation affecting selectin ligands

Abstract Selectins are carbohydrate-binding adhesion molecules that are required for leukocyte trafficking to secondary lymphoid organs and to sites of infection. They interact with fucosylated and sialylated ligands bearing sialyl-Lewis X as a minimal carbohydrate structure. With this in mind, it s...

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Bibliographic Details
Main Authors: Lühn, K, Wild, M
Format: Conference item
Published: 2012