Coreceptors and TCR signaling — the strong and the weak of it

Coreceptors and TCR signaling — the strong and the weak of it

The T-cell coreceptors CD4 and CD8 have well-characterized and essential roles in thymic development, but how they contribute to immune responses in the periphery is unclear. Coreceptors strengthen T-cell responses by many orders of magnitude – beyond a millionfold according to some estimates – but...

Bibliografiset tiedot
Päätekijät:	Mørch, AM, Bálint, Š, Santos, AM, Davis, SJ, Dustin, ML
Aineistotyyppi:	Journal article
Kieli:	English
Julkaistu:	Frontiers Media 2020

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