Ebselen has lithium‐like effects on central 5‐HT2A receptor function

Ebselen has lithium‐like effects on central 5‐HT2A receptor function

<strong>Background and Purpose</strong> Lithium's antidepressant action may be mediated by inhibition of inositol monophosphatase (IMPase), a key enzyme in Gq‐protein coupled receptor signalling. Recently, the antioxidant agent ebselen was identified as an IMPase inhibitor. Here, we...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों:	Antoniadou, I, Kouskou, M, Arsiwala, T, Singh, N, Vasudevan, SR, Fowler, T, Cadirci, E, Churchill, GC, Sharp, T
स्वरूप:	Journal article
भाषा:	English
प्रकाशित:	Wiley 2018

समान संसाधन

Behavioural characterisation of ebselen; a potential lithium-mimetic
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प्रकाशित: (2014)

Ebselen as a novel IMPase inhibitor as a lithium mimetic
द्वारा: Churchill, G, और अन्य
प्रकाशित: (2014)

Effects of the potential lithium-mimetic, ebselen, on impulsivity and emotional processing
द्वारा: Masaki, C, और अन्य
प्रकाशित: (2016)

Investigation of the neurochemical, molecular and behavioural properties of the putative lithium-mimetic, ebselen
द्वारा: Antoniadou, I
प्रकाशित: (2015)

The putative lithium-mimetic ebselen reduces impulsivity in rodent models
द्वारा: Barkus, C, और अन्य
प्रकाशित: (2018)

Effect of the Putative Lithium Mimetic Ebselen on Brain Myo-Inositol, Sleep, and Emotional Processing in Humans
द्वारा: Singh, N, और अन्य
प्रकाशित: (2015)

Effect of the putative lithium mimetic ebselen on brain myo-inositol, sleep, and emotional processing in humans
द्वारा: Singh, N, और अन्य
प्रकाशित: (2016)

Effects of the potential lithium-mimetic, ebselen, on brain neurochemistry: a magnetic resonance spectroscopy study at 7 tesla
द्वारा: Masaki, C, और अन्य
प्रकाशित: (2016)

Evidence that 5-HT2 receptor agonist induced inhibtion of 5-HT cell firing is mediated by central and not peripheral 5-HT2 receptors
द्वारा: Boothman, L, और अन्य
प्रकाशित: (2003)

A safe lithium mimetic for bipolar disorder.
द्वारा: Singh, N, और अन्य
प्रकाशित: (2013)

The effect of lithium on 5-HT-mediated neuroendocrine responses and platelet 5-HT receptors.
द्वारा: Glue, P, और अन्य
प्रकाशित: (1986)

Identification of lithium mimetic that inhibits inositol monophosphatase for the treatment of bipolar disorder
द्वारा: Singh, N, और अन्य
प्रकाशित: (2011)

Evidence that central 5-HT2A and 5-HT2B/C receptors regulate 5-HT cell firing in the dorsal raphe nucleus of the anaesthetised rat.
द्वारा: Boothman, L, और अन्य
प्रकाशित: (2003)

Investigating the effects of the lithium-mimetic drug, ebselen, on emotional processing and brain neurochemistry in patients with medication-resistant depression
द्वारा: Ramli, FF
प्रकाशित: (2024)

The potential use of ebselen in treatment-resistant depression
द्वारा: Ramli, FF, और अन्य
प्रकाशित: (2022)

Is Ebselen A Therapeutic Target in Fracture Healing?
द्वारा: Ahmet Kose, और अन्य
प्रकाशित: (2020-06-01)

The Potential Use of Ebselen in Treatment-Resistant Depression
द्वारा: Fitri Fareez Ramli, और अन्य
प्रकाशित: (2022-04-01)

Chemistry Related to the Catalytic Cycle of the Antioxidant Ebselen
द्वारा: Kai N. Sands, और अन्य
प्रकाशित: (2023-04-01)

Expression of 5-HT receptors and the 5-HT transporter in rat brain after electroconvulsive shock.
द्वारा: Burnet, P, और अन्य
प्रकाशित: (1999)

Ebselen and Analogues: Pharmacological Properties and Synthetic Strategies for Their Preparation
द्वारा: Claudio Santi, और अन्य
प्रकाशित: (2021-07-01)

Ebselen Interferes with Alzheimer’s Disease by Regulating Mitochondrial Function
द्वारा: Xuexia Li, और अन्य
प्रकाशित: (2022-07-01)

Convergent Synthesis of Two Fluorescent Ebselen-Coumarin Heterodimers
द्वारा: Jim Küppers, और अन्य
प्रकाशित: (2016-07-01)

Repurposing ebselen for decolonization of vancomycin-resistant enterococci (VRE).
द्वारा: Ahmed AbdelKhalek, और अन्य
प्रकाशित: (2018-01-01)

A possible role for 5-HT2C receptors in postsynaptic feedback regulation of 5 HT neurones
द्वारा: Raley, J, और अन्य
प्रकाशित: (2006)

Effects of the 5-HT(4) receptor agonist RS67333 and paroxetine on hippocampal extracellular 5-HT levels.
द्वारा: Licht, C, और अन्य
प्रकाशित: (2010)

Metallocenyl derivatives of ebselen are selective and competitive inhibitors of thioredoxin reductase
द्वारा: Koh, Wei Xiang, और अन्य
प्रकाशित: (2022)

The Effectiveness of Ebselen in Facial Nerve Crush Injury: An Experimental Study
द्वारा: Lütfü Şeneldir, और अन्य
प्रकाशित: (2024-11-01)

Ebselen Optimized the Therapeutic Effects of Silver Nanoparticles for Periodontal Treatment
द्वारा: Liang Y, और अन्य
प्रकाशित: (2023-12-01)

Repurposing Clinical Molecule Ebselen to Combat Drug Resistant Pathogens.
द्वारा: Shankar Thangamani, और अन्य
प्रकाशित: (2015-01-01)

In Vitro Anti-Prostate Cancer Activity of Two Ebselen Analogues
द्वारा: Katarzyna B. Kaczor-Keller, और अन्य
प्रकाशित: (2020-03-01)

Discovery of Ebselen as an Inhibitor of 6PGD for Suppressing Tumor Growth
द्वारा: Feng Q, और अन्य
प्रकाशित: (2020-08-01)

Evidence that genetic variation in 5-HT transporter expression is linked to changes in 5-HT2A receptor function.
द्वारा: Jennings, K, और अन्य
प्रकाशित: (2008)

Mice over-expressing the 5-HT transporter show evidence of increased central 5-HT2A function
द्वारा: Jennings, K, और अन्य
प्रकाशित: (2003)

Identification of ebselen and its analogues as potent covalent inhibitors of papain-like protease from SARS-CoV-2
द्वारा: Ewelina Weglarz-Tomczak, और अन्य
प्रकाशित: (2021-02-01)

Lithium increases slow wave sleep: possible mediation by brain 5-HT2 receptors?
द्वारा: Friston, K, और अन्य
प्रकाशित: (1989)

Lithium and 5-HT1A receptor sensitivity: a neuroendocrine study in healthy volunteers.
द्वारा: Walsh, A, और अन्य
प्रकाशित: (1991)

In Vitro Efficacy of Ebselen and BAY 11-7082 Against Naegleria fowleri
द्वारा: Anjan Debnath, और अन्य
प्रकाशित: (2018-03-01)

The Assessment on Synergistic Activity of Ebselen and Silver Ion Against Yersinia pseudotuberculosis
द्वारा: Chuanjiang Dong, और अन्य
प्रकाशित: (2022-07-01)

Synthesis of new alkylated and methoxylated analogues of ebselen with antiviral and antimicrobial properties
द्वारा: Magdalena Piętka-Ottlik, और अन्य
प्रकाशित: (2017-02-01)

Developing selective histone deacetylases (HDACs) inhibitors through ebselen and analogs
द्वारा: Wang Y, और अन्य
प्रकाशित: (2017-05-01)