The molecular mechanism of nitrogen-containing bisphosphonates as antiosteoporosis drugs.

Osteoporosis and low bone mass are currently estimated to be a major public health risk affecting >50% of the female population over the age of 50. Because of their bone-selective pharmacokinetics, nitrogen-containing bisphosphonates (N-BPs), currently used as clinical inhibitors of bone-reso...

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Bibliographic Details
Main Authors: Kavanagh, K, Guo, K, Dunford, J, Wu, X, Knapp, S, Ebetino, F, Rogers, M, Russell, R, Oppermann, U
Format: Journal article
Language:English
Published: 2006