Independent mechanisms target SMCHD1 to trimethylated histone H3 lysine 9-modified chromatin and the inactive X chromosome

Independent mechanisms target SMCHD1 to trimethylated histone H3 lysine 9-modified chromatin and the inactive X chromosome

The chromosomal protein SMCHD1 plays an important role in epigenetic silencing at diverse loci, including the inactive X chromosome, imprinted genes, and the Facioscapulohumeral muscular dystrophy locus. Although homology with canonical SMC family proteins suggests a role in chromosome organization,...

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Bibliographic Details
Main Authors:	Brideau, N, Coker, H, Gendrel, A, Siebert, C, Bezstarosti, K, Demmers, J, Poot, R, Nesterova, T, Brockdorff, N
Format:	Journal article
Published:	American Society for Microbiology 2015

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