Interventions to improve vitamin D status in at-risk ethnic groups during pregnancy and early childhood - a systematic review

<p><strong>Objective:</strong> Systematically review the literature with the primary aim of identifying behavioural interventions to improve vitamin D stores in children from at-risk ethnic groups.</p> <p><strong>Design:</strong> Review based on PRISMA guid...

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Bibliographic Details
Main Authors: Tanna, N, Alexander, EC, Lee, C, Lakhanpaul, M, Popat, R, Almeida-Meza, P, Tuck, A, Manikam, L, Blair, M
Format: Journal article
Language:English
Published: Cambridge University Press 2021
Description
Summary:<p><strong>Objective:</strong> Systematically review the literature with the primary aim of identifying behavioural interventions to improve vitamin D stores in children from at-risk ethnic groups.</p> <p><strong>Design:</strong> Review based on PRISMA guidelines. PROSPERO registration number: CRD42017080932. Health Behaviour model and Behaviour Change Wheel Framework constructs used to underpin evaluation of interventions. Methodological quality evaluated using Cochrane Risk of Bias, Cochrane ROBINS-I, and NHLBI tools.</p> <p><strong>Setting:</strong> Databases Cochrane Library, MEDLINE, EMBASE, CINAHL with secondary search of Google Scholar. No country limits set. Papers between 1990-February 2018, published in English included. Anticipating study heterogeneity, outcome measures not pre-specified and identified from individual full papers. Updated literature search November 2020.</p> <p><strong>Participants:</strong> Patient or population including pregnant women, new-borns and children aged under 18 years, from Asian or African ethnic groups.</p> <p><strong>Results:</strong> Of 10,690 articles screened, 298 underwent full text review, with 24 ultimately included for data extraction. All identified studies conducted a vitamin D pharmacological supplementation intervention, with two also incorporating a behavioural intervention strategy. No study explicitly defined a primary aim of evaluating a behavioural intervention, undertaken to study its effect on Vitamin D supplement uptake.</p> <p><strong>Conclusions:</strong> There is a need to address the paucity of data in ethnic at-risk children on how behavioural interventions, ideally developed and co-produced with the community under study, affect and help improve Vitamin D uptake, within the ante-natal and pregnancy phase as well as during childhood.</p>