Matrix-targeting immunotherapy controls tumor growth and spread by switching macrophage phenotype
The interplay between cancer cells and immune cells is a key determinant of tumor survival. Here, we uncovered how tumors exploit the immuno-modulatory properties of the extracellular matrix to create a microenvironment that enables their escape from immune surveillance. Using orthotopic grafting o...
Main Authors: | Deligny, C, Murdamoothoo, D, Gammage, A, Gschwandtner, M, Midwood, K |
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Format: | Journal article |
Language: | English |
Published: |
American Association for Cancer Research
2020
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