Biological consequences of potential repair intermediates of clustered base damage site in Escherichia coli.
Clustered DNA damage induced by a single radiation track is a unique feature of ionizing radiation. Using a plasmid-based assay in Escherichia coli, we previously found significantly higher mutation frequencies for bistranded clusters containing 7,8-dihydro-8-oxoguanine (8-oxoG) and 5,6-dihydrothymi...
Main Authors: | Shikazono, N, O'Neill, P |
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Format: | Journal article |
Language: | English |
Published: |
2009
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