Rational Zika vaccine design via the modulation of antigen membrane anchors in chimpanzee adenoviral vectors

Rational Zika vaccine design via the modulation of antigen membrane anchors in chimpanzee adenoviral vectors

Zika virus (ZIKV) emerged on a global scale and no licensed vaccine ensures long-lasting anti-ZIKV immunity. Here we report the design and comparative evaluation of four replication-deficient chimpanzee adenoviral (ChAdOx1) ZIKV vaccine candidates comprising the addition or deletion of precursor mem...

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প্রধান লেখক: López-Camacho, C, Abbink, P, Larocca, R, Dejnirattisai, W, Boyd, M, Badamchi-Zadeh, A, Wallace, Z, Doig, J, Velazquez, R, Neto, R, Coelho, D, Kim, Y, Donald, C, Owsianka, A, De Lorenzo, G, Kohl, A, Gilbert, S, Dorrell, L, Mongkolsapaya, J, Patel, A, Screaton, G, Barouch, D, Hill, A, Reyes-Sandoval, A
বিন্যাস: Journal article
প্রকাশিত: Nature Publishing Group 2018

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