Rational Zika vaccine design via the modulation of antigen membrane anchors in chimpanzee adenoviral vectors

Zika virus (ZIKV) emerged on a global scale and no licensed vaccine ensures long-lasting anti-ZIKV immunity. Here we report the design and comparative evaluation of four replication-deficient chimpanzee adenoviral (ChAdOx1) ZIKV vaccine candidates comprising the addition or deletion of precursor mem...

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Hlavní autoři:	López-Camacho, C, Abbink, P, Larocca, R, Dejnirattisai, W, Boyd, M, Badamchi-Zadeh, A, Wallace, Z, Doig, J, Velazquez, R, Neto, R, Coelho, D, Kim, Y, Donald, C, Owsianka, A, De Lorenzo, G, Kohl, A, Gilbert, S, Dorrell, L, Mongkolsapaya, J, Patel, A, Screaton, G, Barouch, D, Hill, A, Reyes-Sandoval, A
Médium:	Journal article
Vydáno:	Nature Publishing Group 2018

Rational Zika vaccine design via the modulation of antigen membrane anchors in chimpanzee adenoviral vectors

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