Towards optimal regimens of parenteral quinine for young African children with cerebral malaria: the importance of unbound quinine concentration.

Towards optimal regimens of parenteral quinine for young African children with cerebral malaria: the importance of unbound quinine concentration.

Young African children with severe malaria are given quinine using a regimen designed for Thai adults. We measured quinine in the blood, plasma and plasma water of young children in Kenya after rapid intravenous and intramuscular dosing, and calculated the therapeutic range of unbound quinine. The p...

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Dades bibliogràfiques
Autors principals:	Winstanley, P, Newton, C, Watkins, W, Mberu, E, Ward, S, Warn, P, Mwangi, I, Waruiru, C, Pasvol, G, Warrell, D
Format:	Journal article
Idioma:	English
Publicat:	1993

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