Effects of pregnancy planning, fertility, and assisted reproductive treatment on child behavioral problems at 5 and 7 years: evidence from the Millennium Cohort Study.
OBJECTIVE: To examine the effects of pregnancy planning, time to conception (TTC), and assisted reproductive technologies (ART) on child behavior. DESIGN: Prospective cohort study. SETTING: Not applicable. PATIENT(S): A total of 12,380 singletons recruited at 9 months and followed-up at 5 and 7 yea...
| Main Authors: | , , , , , |
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| Format: | Journal article |
| Language: | English |
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2013
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| _version_ | 1797084036390191104 |
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| author | Carson, C Redshaw, M Sacker, A Kelly, Y Kurinczuk, J Quigley, M |
| author_facet | Carson, C Redshaw, M Sacker, A Kelly, Y Kurinczuk, J Quigley, M |
| author_sort | Carson, C |
| collection | OXFORD |
| description | OBJECTIVE: To examine the effects of pregnancy planning, time to conception (TTC), and assisted reproductive technologies (ART) on child behavior. DESIGN: Prospective cohort study. SETTING: Not applicable. PATIENT(S): A total of 12,380 singletons recruited at 9 months and followed-up at 5 and 7 years. Conceptions were divided into "unplanned" (unplanned, unhappy), "mistimed" (unplanned, happy), "planned" (planned, TTC <12 months), "subfertile" (planned, TTC ≥ 12 months), "ovulation induced" (received clomiphene citrate), and "ART" (IVF or intracytoplasmic sperm injection). INTERVENTION(S): None. MAIN OUTCOME MEASURE(S): Child behavior (Strengths and Difficulties Questionnaire [SDQ]). RESULT(S): Mistimed and unplanned children had higher average SDQ scores at age 5 and 7 years and were significantly more likely to have a clinically relevant behavioral problem compared with the planned group. The ART children had significantly higher average SDQ scores at both 5 and 7 years compared with the planned group. An increase in clinically relevant behavioral problems was observed at 5 years (odds ratio 2.05 [95% confidence interval 0.96, 4.42]) but failed to reach statistical significance. No effects were observed in the subfertile and ovulation-induced groups. CONCLUSION(S): Unplanned and mistimed children exhibit more behavioral problems than their planned peers. Though ART children have higher mean total difficulties scores, this did not translate into a statistically significant increase in clinically relevant behavioral problems. |
| first_indexed | 2024-03-07T01:50:00Z |
| format | Journal article |
| id | oxford-uuid:99c19de8-7dae-4ea5-8e3a-be0e69200850 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T01:50:00Z |
| publishDate | 2013 |
| record_format | dspace |
| spelling | oxford-uuid:99c19de8-7dae-4ea5-8e3a-be0e692008502022-03-27T00:16:36ZEffects of pregnancy planning, fertility, and assisted reproductive treatment on child behavioral problems at 5 and 7 years: evidence from the Millennium Cohort Study.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:99c19de8-7dae-4ea5-8e3a-be0e69200850EnglishSymplectic Elements at Oxford2013Carson, CRedshaw, MSacker, AKelly, YKurinczuk, JQuigley, M OBJECTIVE: To examine the effects of pregnancy planning, time to conception (TTC), and assisted reproductive technologies (ART) on child behavior. DESIGN: Prospective cohort study. SETTING: Not applicable. PATIENT(S): A total of 12,380 singletons recruited at 9 months and followed-up at 5 and 7 years. Conceptions were divided into "unplanned" (unplanned, unhappy), "mistimed" (unplanned, happy), "planned" (planned, TTC <12 months), "subfertile" (planned, TTC ≥ 12 months), "ovulation induced" (received clomiphene citrate), and "ART" (IVF or intracytoplasmic sperm injection). INTERVENTION(S): None. MAIN OUTCOME MEASURE(S): Child behavior (Strengths and Difficulties Questionnaire [SDQ]). RESULT(S): Mistimed and unplanned children had higher average SDQ scores at age 5 and 7 years and were significantly more likely to have a clinically relevant behavioral problem compared with the planned group. The ART children had significantly higher average SDQ scores at both 5 and 7 years compared with the planned group. An increase in clinically relevant behavioral problems was observed at 5 years (odds ratio 2.05 [95% confidence interval 0.96, 4.42]) but failed to reach statistical significance. No effects were observed in the subfertile and ovulation-induced groups. CONCLUSION(S): Unplanned and mistimed children exhibit more behavioral problems than their planned peers. Though ART children have higher mean total difficulties scores, this did not translate into a statistically significant increase in clinically relevant behavioral problems. |
| spellingShingle | Carson, C Redshaw, M Sacker, A Kelly, Y Kurinczuk, J Quigley, M Effects of pregnancy planning, fertility, and assisted reproductive treatment on child behavioral problems at 5 and 7 years: evidence from the Millennium Cohort Study. |
| title | Effects of pregnancy planning, fertility, and assisted reproductive treatment on child behavioral problems at 5 and 7 years: evidence from the Millennium Cohort Study. |
| title_full | Effects of pregnancy planning, fertility, and assisted reproductive treatment on child behavioral problems at 5 and 7 years: evidence from the Millennium Cohort Study. |
| title_fullStr | Effects of pregnancy planning, fertility, and assisted reproductive treatment on child behavioral problems at 5 and 7 years: evidence from the Millennium Cohort Study. |
| title_full_unstemmed | Effects of pregnancy planning, fertility, and assisted reproductive treatment on child behavioral problems at 5 and 7 years: evidence from the Millennium Cohort Study. |
| title_short | Effects of pregnancy planning, fertility, and assisted reproductive treatment on child behavioral problems at 5 and 7 years: evidence from the Millennium Cohort Study. |
| title_sort | effects of pregnancy planning fertility and assisted reproductive treatment on child behavioral problems at 5 and 7 years evidence from the millennium cohort study |
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