Intercontinental spread of pyrimethamine-resistant malaria.
Here we present molecular evidence demonstrating that malaria parasites bearing high-level pyrimethamine resistance originally arrived in Africa from southeast Asia. The resistance alleles carried by these migrants are now spreading across Africa at an alarming rate, signaling the end of affordable...
| Main Authors: | , , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2004
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| _version_ | 1797084046389411840 |
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| author | Roper, C Pearce, R Nair, S Sharp, B Nosten, F Anderson, T |
| author_facet | Roper, C Pearce, R Nair, S Sharp, B Nosten, F Anderson, T |
| author_sort | Roper, C |
| collection | OXFORD |
| description | Here we present molecular evidence demonstrating that malaria parasites bearing high-level pyrimethamine resistance originally arrived in Africa from southeast Asia. The resistance alleles carried by these migrants are now spreading across Africa at an alarming rate, signaling the end of affordable malaria treatment and presenting sub-Saharan Africa with a public health crisis. |
| first_indexed | 2024-03-07T01:50:09Z |
| format | Journal article |
| id | oxford-uuid:99cf9a99-cc49-4cc4-8261-83a1dceaa01a |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T01:50:09Z |
| publishDate | 2004 |
| record_format | dspace |
| spelling | oxford-uuid:99cf9a99-cc49-4cc4-8261-83a1dceaa01a2022-03-27T00:17:00ZIntercontinental spread of pyrimethamine-resistant malaria.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:99cf9a99-cc49-4cc4-8261-83a1dceaa01aEnglishSymplectic Elements at Oxford2004Roper, CPearce, RNair, SSharp, BNosten, FAnderson, THere we present molecular evidence demonstrating that malaria parasites bearing high-level pyrimethamine resistance originally arrived in Africa from southeast Asia. The resistance alleles carried by these migrants are now spreading across Africa at an alarming rate, signaling the end of affordable malaria treatment and presenting sub-Saharan Africa with a public health crisis. |
| spellingShingle | Roper, C Pearce, R Nair, S Sharp, B Nosten, F Anderson, T Intercontinental spread of pyrimethamine-resistant malaria. |
| title | Intercontinental spread of pyrimethamine-resistant malaria. |
| title_full | Intercontinental spread of pyrimethamine-resistant malaria. |
| title_fullStr | Intercontinental spread of pyrimethamine-resistant malaria. |
| title_full_unstemmed | Intercontinental spread of pyrimethamine-resistant malaria. |
| title_short | Intercontinental spread of pyrimethamine-resistant malaria. |
| title_sort | intercontinental spread of pyrimethamine resistant malaria |
| work_keys_str_mv | AT roperc intercontinentalspreadofpyrimethamineresistantmalaria AT pearcer intercontinentalspreadofpyrimethamineresistantmalaria AT nairs intercontinentalspreadofpyrimethamineresistantmalaria AT sharpb intercontinentalspreadofpyrimethamineresistantmalaria AT nostenf intercontinentalspreadofpyrimethamineresistantmalaria AT andersont intercontinentalspreadofpyrimethamineresistantmalaria |