Probing the penicillin sidechain selectivity of recombinant deacetoxycephalosporin C synthase.
Deacetoxycephalosporin C synthase from Streptomyces clavuligerus catalyses the conversion of the five-membered penicillin ring to the unsaturated six-membered cephem ring of deacetoxycephalosporin C. The effects on enzyme activity of the penicillin substrate sidechain and various cofactors were inve...
Κύριοι συγγραφείς: | , , , , , |
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Μορφή: | Journal article |
Γλώσσα: | English |
Έκδοση: |
2001
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