Sulfadoxine-pyrimethamine pharmacokinetics in malaria: pediatric dosing implications.

OBJECTIVE: Our objective was to characterize the pharmacokinetic properties of sulfadoxine-pyrimethamine in African adults and children with acute falciparum malaria. Despite decades of widespread use, there are few data to inform dose recommendations. METHODS: In a prospective multicenter pharmaco...

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Bibliographic Details
Main Authors: Barnes, K, Little, F, Smith, P, Evans, A, Watkins, WM, White, N
Format: Journal article
Language:English
Published: 2006