Naturally exposed populations differ in their T1 and T2 responses to the circumsporozoite protein of Plasmodium falciparum.

T-cell responses directed against the circumsporozoite protein (CS) of Plasmodium falciparum can mediate protection against malaria. We determined the frequency of T cells reactive to different regions of the CS in the blood of donors naturally exposed to P. falciparum by examining T1 (gamma interfe...

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Bibliographic Details
Main Authors: Reece, W, Plebanski, M, Akinwunmi, P, Gothard, P, Flanagan, K, Lee, E, Cortina-Borja, M, Hill, A, Pinder, M
Format: Journal article
Language:English
Published: 2002