General pyrrolidine synthesis via iridium-catalyzed reductive azomethine ylide generation from tertiary amides and lactams

An iridium-catalyzed reductive generation of both stabilized and unstabilized azomethine ylides and their application to functionalized pyrrolidine synthesis via [3 + 2] dipolar cycloaddition reactions is described. Proceeding under mild reaction conditions from both amide and lactam precursors poss...

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Príomhchruthaitheoirí: Yamazaki, K, Gabriel, P, Di Carmine, G, Pedroni, J, Farizyan, M, Hamlin, TA, Dixon, DJ
Formáid: Journal article
Teanga:English
Foilsithe / Cruthaithe: American Chemical Society 2021