A general reaction-diffusion model of acidity in cancer invasion.

We model the metabolism and behaviour of a developing cancer tumour in the context of its microenvironment, with the aim of elucidating the consequences of altered energy metabolism. Of particular interest is the Warburg Effect, a widespread preference in tumours for cytosolic glycolysis rather than...

Full description

Bibliographic Details
Main Authors: McGillen, J, Gaffney, E, Martin, N, Maini, P
Format: Journal article
Language:English
Published: 2014